ArticleCirculation. Heart failure2024
Pulmonary Artery Pressures and Mortality During Venoarterial ECMO: An ELSO Registry Analysis.
Article in Circulation. Heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Differential biventricular responses to VA-ECMO flow ramping after cardiac arrest: establishment of a preclinical ECPR model with PV loop monitoring.Resuscitation plus · 2025Article
- Cardiovascular Physiology During Mechanical Circulatory Support: Implications for Management and Monitoring.Journal of clinical medicine · 2025Review
- The effect of antifibrotics on the progression of pulmonary hypertension in patients with interstitial lung disease listed for lung transplantation.BMC pulmonary medicine · 2025Article
- Filter-type neural network-based counter-pulsation control in pulsatile ECMO: improving heartbeat-pulse discrimination and synchronization accuracy.Biomedical engineering online · 2025Article
- Redefining weaning in a VA ECMO: a case report on pump-controlled retrograde trial off.Indian journal of thoracic and cardiovascular surgery · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundSystemic hemodynamics and specific ventilator settings have been shown to predict survival during venoarterial extracorporeal membrane oxygenation (ECMO). How the right heart (the right ventricle and pulmonary artery) affect survival during venoarterial ECMO is unknown. We aimed to identify the relationship between right heart function with mortality and the duration of ECMO support.
methodsCardiac ECMO runs in adults from the Extracorporeal Life Support Organization Registry between 2010 and 2022 were queried. Right heart function was quantified via pulmonary artery pulse pressure (PAPP) for pre-ECMO and on-ECMO periods. A multivariable model was adjusted for modified Society for Cardiovascular Angiography and Interventions stage, age, sex, and concurrent clinical data (ie, pulmonary vasodilators and systemic pulse pressure). The primary outcome was in-hospital mortality.
resultsA total of 4442 ECMO runs met inclusion criteria and had documentation of hemodynamic and illness severity variables. The mortality rate was 55%; nonsurvivors were more likely to be older, have a worse Society for Cardiovascular Angiography and Interventions stage, and have longer pre-ECMO endotracheal intubation times (
conclusionsEarly on-ECMO right heart function and interval improvement from pre-ECMO values were associated with mortality reduction during cardiac ECMO. Incorporation of right heart metrics into risk prediction models should be considered.
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