Evidence map›Paper›PMID 38979591›Full record

ReviewPathologica2024

Non-C19MC-altered embryonal tumor with multilayered rosettes in a young woman with DICER1 syndrome: case report and review of the literature.

María Concepción Campos Mármol, María Aguado, Teresa Ramón Y Cajal, Alberto Gallardo, Luis Catasús, Allan Gonzalez, Jorge Eliecer Méndez, Adriana Lasa, Montse Arumi, Oscar Gallego Rubio and 5 more

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PubMed Full text at PMC Publisher
In one paragraph

Review in Pathologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

María Concepción Campos MármolDepartment of Pathology, Hospital General de Granollers, Granollers, Spain.
María AguadoDepartment of Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Teresa Ramón Y CajalGenetic Counselling Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Alberto GallardoDepartment of Pathology, Hospital de la Santa Creu i Sant Pau, Institute of Biomedical Research (IIB Sant Pau), Autonomous University of Barcelona, Barcelona, Spain.
Luis CatasúsDepartment of Pathology, Hospital de la Santa Creu i Sant Pau, Institute of Biomedical Research (IIB Sant Pau), Autonomous University of Barcelona, Barcelona, Spain.
Allan GonzalezDepartment of Pathology, Hospital de la Santa Creu i Sant Pau, Institute of Biomedical Research (IIB Sant Pau), Autonomous University of Barcelona, Barcelona, Spain.
Jorge Eliecer MéndezDepartment of Radiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Adriana LasaDepartment of Genetics, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Montse ArumiDepartment of Pathology, Hospital del Mar, Barcelona, Spain.
Oscar Gallego RubioDepartment of Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Josep Balart SerraDepartment of Radiotherapeutic Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Fernando Muñoz HernandezDepartment of Neurosurgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Andreas von DeimlingDepartment of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany and Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Felix K F KommossDepartment of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Iñigo EspinosaDepartment of Pathology, Hospital de la Santa Creu i Sant Pau, Institute of Biomedical Research (IIB Sant Pau), Autonomous University of Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embryonal tumors with multilayered rosettes (ETMR) are highly aggressive and therapy-resistant pediatric central nervous system (CNS) tumors that have three histological patters: embryonal tumor with abundant neuropil and true rosettes, ependymoblastoma, and medulloepithelioma. We present a case of ETMR in an 18-year-old woman with DICER1 syndrome. This report confirms the important role of DNA-methylation analysis in the classification of CNS embryonal tumors and the importance of investigating somatic and germline DICER1 mutations in all CNS embryonal tumors.

Indexed as

DEAD-box RNA HelicasesNeoplasms, Germ Cell and EmbryonalRibonuclease IIIAdolescentDNA MethylationFemaleHumansDEAD-box RNA HelicasesDICER1 protein, humanRibonuclease IIIDICER1, DNA methylation-based CNS tumor classifierDICER1 syndromeembryonal tumor with multilayered rosettes

Identifiers

PMID38979591
PMCPMC11447652

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.