Evidence map›Paper›PMID 38979590›Full record

ReviewPathologica2024

SMARCB1/INI1-deficient undifferentiated tumour of the thorax: a case report and review of the literature.

Moreno Zagni, Alessandro Marando, Mariachiara Negrelli, Calogero Lauricella, Valentina Motta, Giulia Paglino, Silvio Veronese, Emanuele Valtorta, Emanuela Bonoldi, Giuseppe Pelosi

Abstract readCase ReportsReview
In one paragraph

Review in Pathologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Moreno ZagniPostgraduate School of Pathology, University of Milan, Milan, Italy.
Alessandro MarandoDepartment of Surgical Pathology, Niguarda Hospital, Milano, Italy.
Mariachiara NegrelliPostgraduate School of Pathology, University of Milan, Milan, Italy.
Calogero LauricellaDepartment of Surgical Pathology, Niguarda Hospital, Milano, Italy.
Valentina MottaDepartment of Surgical Pathology, Niguarda Hospital, Milano, Italy.
Giulia PaglinoDepartment of Surgical Pathology, Niguarda Hospital, Milano, Italy.
Silvio VeroneseDepartment of Surgical Pathology, Niguarda Hospital, Milano, Italy.
Emanuele ValtortaDepartment of Surgical Pathology, Niguarda Hospital, Milano, Italy.
Emanuela BonoldiDepartment of Surgical Pathology, Niguarda Hospital, Milano, Italy.
Giuseppe PelosiPostgraduate School of Pathology, University of Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 5th WHO classification of thoracic tumours includes thoracic SMARCA4-deficient undifferentiated tumour (SMARCA4-UT) among the "other epithelial tumours of the lung" chapter. Herein, we present a case of undifferentiated thoracic neoplasm with retention of SMARCA4 expression, lack of NUT fusion protein and loss of SMARCB1/INI1 expression. After presenting the clinical and pathological features of the tumour, we carried out a review of the literature on the same topic. Albeit very rare, we believe this entity should be included in the heterogeneous group of undifferentiated neoplasms of the thorax.

Indexed as

DNA HelicasesSMARCB1 ProteinThoracic NeoplasmsTranscription FactorsBiomarkers, TumorHumansLung NeoplasmsNuclear ProteinsBiomarkers, TumorDNA HelicasesNuclear ProteinsSMARCA4 protein, humanSMARCB1 ProteinSMARCB1 protein, humanTranscription FactorsSMARCA4-deficient undifferentiated tumourSMARCB1-deficient undifferentiated tumourSWI/SNF complexthoracic undifferentiated tumours

Identifiers

PMID38979590
PMCPMC11447651

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.