Evidence map›Paper›PMID 38979520›Full record

ArticleDermatology reports2024

Hydroxychloroquine-induced generalized myopathy in a patient with lupus tumidus: a case report.

Alice Verdelli, Daniela Massi, Vincenza Maio, Gabriele Cavazza, Alberto Corrà, Elena Biancamaria Mariotti, Lavinia Quintarelli, Valentina Ruffo di Calabria, Cristina Aimo, Emiliano Antiga and 1 more

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Article in Dermatology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Alice VerdelliRare Dermatological Diseases Unit, Department of Health Sciences, Toscana Centro Local Health Unit, Florence; European Reference Network Skin Member.
Daniela MassiSection of Pathology.
Vincenza MaioSection of Pathology.
Gabriele CavazzaSection of Dermatology, Department of Health Sciences, University of Florence, Italy.
Alberto CorràRare Dermatological Diseases Unit, Department of Health Sciences, Toscana Centro Local Health Unit, Florence; European Reference Network Skin Member.
Elena Biancamaria MariottiSection of Dermatology, Department of Health Sciences, University of Florence, Italy.
Lavinia QuintarelliRare Dermatological Diseases Unit, Department of Health Sciences, Toscana Centro Local Health Unit, Florence; European Reference Network Skin Member.
Valentina Ruffo di CalabriaSection of Dermatology, Department of Health Sciences, University of Florence, Italy.
Cristina AimoSection of Dermatology, Department of Health Sciences, University of Florence, Italy.
Emiliano AntigaSection of Dermatology, Department of Health Sciences, University of Florence, Italy.
Marzia CaproniRare Dermatological Diseases Unit, Department of Health Sciences, Toscana Centro Local Health Unit, Florence; European Reference Network Skin Member.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A subtype of cutaneous lupus erythematosus known as lupus erythematosus tumidus (LET) is characterized by sun-exposed areas that typically display urticaria-like papules and plaques. For LET, systemic therapy with antimalarials - particularly hydroxychloroquine (HCQ) - is the first line of treatment. Even though the safety profile of these medications appears to be high, there have been very few reports of side effects in the literature, including hemolytic anemia, retinal toxicity, maculopapular rash, gastrointestinal disturbance, and blue-gray discoloration of the skin or mucous membranes. Here, we report a unique instance of a 46-year-old LET smoker who, following HCQ treatment, developed a generalized myopathy.

Indexed as

cutaneous lupus erythematosusdrug reactionhydrox-ychloroquine-induced myopathylupus tumidustacrolimus ointment

Identifiers

PMID38979520
PMCPMC11228567

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