Evidence map›Paper›PMID 38979510›Full record

ArticleFrontiers in cellular and infection microbiology2024

Phylogenetic and mutational analysis of H10N3 avian influenza A virus in China: potential threats to human health.

Jingyi Dai, Jun Zhao, Jiawei Xia, Pei Zhang, Yadi Ding, Qiujing Li, Min Hou, Xianhui Xiong, Qianqi Jian, Yanyan Liu and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingyi Dai *Department of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, China.
Jun Zhao *School of Public Health, Hubei University of Medicine, Shiyan, China.
Jiawei Xia *Department of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, China.
Pei ZhangDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, China.
Yadi DingDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, China.
Qiujing LiDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, China.
Min HouDepartment of Microbiological Laboratory, Kunming City Center for Disease Control and Prevention, Kunming, China.
Xianhui XiongDepartment of Microbiological Laboratory, Kunming City Center for Disease Control and Prevention, Kunming, China.
Qianqi JianDepartment of Microbiological Laboratory, Kunming City Center for Disease Control and Prevention, Kunming, China.
Yanyan LiuDepartment of Microbiological Laboratory, Kunming City Center for Disease Control and Prevention, Kunming, China.
Guiming LiuDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the avian influenza virus has emerged as a significant threat to both human and public health. This study focuses on a patient infected with the H10N3 subtype of avian influenza virus, admitted to the Third People's Hospital of Kunming City on March 6, 2024. Metagenomic RNA sequencing and polymerase chain reaction (PCR) analysis were conducted on the patient's sputum, confirming the H10N3 infection. The patient presented severe pneumonia symptoms such as fever, expectoration, chest tightness, shortness of breath, and cough. Phylogenetic analysis of the Haemagglutinin (HA) and neuraminidase (NA) genes of the virus showed that the virus was most closely related to a case of human infection with the H10N3 subtype of avian influenza virus found in Zhejiang Province, China. Analysis of amino acid mutation sites identified four mutations potentially hazardous to human health. Consequently, this underscores the importance of continuous and vigilant monitoring of the dynamics surrounding the H10N3 subtype of avian influenza virus, utilizing advanced genomic surveillance techniques.

Indexed as

Hemagglutinin Glycoproteins, Influenza VirusInfluenza A virusInfluenza, HumanNeuraminidasePhylogenyAnimalsBirdsChinaDNA Mutational AnalysisHumansInfluenza in BirdsMaleMutationRNA, ViralSputumViral ProteinsHemagglutinin Glycoproteins, Influenza VirusNA protein, influenza A virusNeuraminidaseRNA, ViralViral Proteinsavian influenza A virusH10N3human infectionmutationphylogeny analysis

Identifiers

PMID38979510
PMCPMC11228180

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.