Evidence map›Paper›PMID 38979501›Full record

SynthesisFrontiers in psychiatry2024

Applications of large language models in psychiatry: a systematic review.

Mahmud Omar, Shelly Soffer, Alexander W Charney, Isotta Landi, Girish N Nadkarni, Eyal Klang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. AI in Medical Questionnaires: Scoping ReviewJournal of medical Internet research · 2025
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  10. Artificial Intelligence-Assisted Generation of Case Scenarios and Multiple-Choice Questions in Psychiatry: A Pilot Study.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahmud OmarFaculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Shelly SofferInternal Medicine B, Assuta Medical Center, Ashdod, Israel.
Alexander W CharneyIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Isotta LandiIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Girish N NadkarniHasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Eyal KlangHasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With their unmatched ability to interpret and engage with human language and context, large language models (LLMs) hint at the potential to bridge AI and human cognitive processes. This review explores the current application of LLMs, such as ChatGPT, in the field of psychiatry. Methods: We followed PRISMA guidelines and searched through PubMed, Embase, Web of Science, and Scopus, up until March 2024. Results: From 771 retrieved articles, we included 16 that directly examine LLMs' use in psychiatry. LLMs, particularly ChatGPT and GPT-4, showed diverse applications in clinical reasoning, social media, and education within psychiatry. They can assist in diagnosing mental health issues, managing depression, evaluating suicide risk, and supporting education in the field. However, our review also points out their limitations, such as difficulties with complex cases and potential underestimation of suicide risks. Conclusion: Early research in psychiatry reveals LLMs' versatile applications, from diagnostic support to educational roles. Given the rapid pace of advancement, future investigations are poised to explore the extent to which these models might redefine traditional roles in mental health care.

Indexed as

artificial intelligencegenerative pre-trained transformer (GPT)large language modelLLMSpsychiatry

Identifiers

PMID38979501
PMCPMC11228775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.