Evidence map›Paper›PMID 38979406›Full record

SynthesisFrontiers in immunology2024

Rational approach to the prescription of anti-rheumatic drugs in rheumatoid arthritis: a product leaflet-based strategy in Italy.

Carlo Perricone, Andrea Castellucci, Giacomo Cafaro, Santina Calvacchi, Lorenza Bruno, Roberto Dal Pozzolo, Francesco Tromby, Anna Colangelo, Roberto Gerli, Elena Bartoloni

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carlo Perricone *Rheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Andrea Castellucci *Rheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Giacomo CafaroRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Santina CalvacchiRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Lorenza BrunoRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Roberto Dal PozzoloRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Francesco TrombyRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Anna ColangeloRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Roberto GerliRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Elena BartoloniRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of patients with rheumatoid arthritis (RA) has dramatically changed in the past 30 years. Currently, numerous conventional, biologic, and targeted synthetic DMARDs have been licensed and used following recommendations provided by international and national scientific societies. However, the availability of biosimilars and the increasing necessity of savings impacted on the local/national prescription of these drugs. The information provided by data sheet of every single drug is a decisive factor on the choice of a certain treatment merged with the patient's profile. Thus, our purpose was to construct a rational algorithm for the treatment strategy in RA according to costs and the product leaflet of the biologic and targeted-synthetic DMARDs currently licensed in Italy. We used the most recent available recommendations and then we performed a review of the literature considering all the factors that are known to influence drug safety/effectiveness. All these factors were considered in the context of the data sheets of currently available originators and biosimilars.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidBiosimilar PharmaceuticalsAlgorithmsDrug LabelingHumansItalyAntirheumatic AgentsBiosimilar PharmaceuticalsDMARDsEULARJAKiproduct leafletrecommendationsrheumatoid arthritistreatment

Identifiers

PMID38979406
PMCPMC11228816

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.