Evidence map›Paper›PMID 38979293›Full record

ArticlebioRxiv : the preprint server for biology2024

Forelimb motor recovery by modulating extrinsic and intrinsic signaling as well as neuronal activity after the cervical spinal cord injury.

Hirohide Takatani, Naoki Fujita, Fumiyasu Imai, Yutaka Yoshida

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Hirohide TakataniBurke Neurological Institute, White Plains, New York, United States.
Naoki FujitaLaboratory of Veterinary Surgery, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Tokyo, Japan.
Fumiyasu ImaiBurke Neurological Institute, White Plains, New York, United States.
Yutaka YoshidaBurke Neurological Institute, White Plains, New York, United States.

Funding

Synapse elimination in the central nervous systemR01NS093002 · NINDS · WINIFRED MASTERSON BURKE MED RES INST · PI YOSHIDA, YUTAKA · 2015 to 2024
$4.6M
Corticospinal Neuron Dysfunction and Degeneration in ALS: Testing the Role of Corticomotor Connectivity in Motor Neuron DiseaseR01NS119508 · NINDS · WINIFRED MASTERSON BURKE MED RES INST · PI SHNEIDER, NEIL ALAN, YOSHIDA, YUTAKA · 2021 to 2025
$3.4M
Indirect Spinal Ascending Pathways to Control Skilled MovementsR01NS115963 · NINDS · WINIFRED MASTERSON BURKE MED RES INST · PI Yutaka Yoshida · 2020 to 2026
$3.3M
A novel combinatorial approach to restore motor function after spinal cord injuryR01NS100772 · NINDS · WINIFRED MASTERSON BURKE MED RES INST · PI YOSHIDA, YUTAKA · 2017 to 2021
$1.9M
Advanced, multi-function, inverted confocal microscope for BNI Structural and Functional Imaging CoreS10OD028547 · OD · WINIFRED MASTERSON BURKE MED RES INST · PI HOLLIS, EDMUND R · 2020 to 2020
$530k
NIH HHS S10 OD028547NINDS NIH HHS R01 NS093002NINDS NIH HHS R01 NS100772NINDS NIH HHS R01 NS115963NINDS NIH HHS R01 NS119508
6 · The paper itself

Abstract

Singular strategies for promoting axon regeneration and motor recovery after spinal cord injury (SCI) have been attempted with limited success. Here, we propose the combinatorial approach of deleting extrinsic and intrinsic factors paired with neural stimulation, will enhance adaptive axonal growth and motor recovery after SCI. We previously showed the deletion of

Identifiers

PMID38979293
PMCPMC11230274

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.