Evidence map›Paper›PMID 38979245›Full record

ArticlebioRxiv : the preprint server for biology2024

Highly Multiplexed Spatial Transcriptomics in Bacteria.

Ari Sarfatis, Yuanyou Wang, Nana Twumasi-Ankrah, Jeffrey R Moffitt

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Ari SarfatisProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115 USA.
Yuanyou WangProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115 USA.
Nana Twumasi-AnkrahProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115 USA.
Jeffrey R MoffittProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115 USA.ORCID 0000-0002-3836-3101

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI JENNIFER W MACK · 1985 to 2026
$330.6M
STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JONATHAN C KAGAN · 1986 to 2026
$32.4M
Rapid, Robust, and Routine: Multiplexed Microscopy for Spatially Resolved Whole-Transcriptomic Single-Cell Profiling and the Construction of Cell Atlases of all Tissues and in all OrganismsR01GM143277 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI MOFFITT, JEFFREY · 2021 to 2024
$1.6M
A spatially resolved single-cell transcriptomic technique for microbial pathogenesisR21AI166230 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI MOFFITT, JEFFREY · 2022 to 2023
$487k
NCI NIH HHS P30 CA006516NIAID NIH HHS R21 AI166230NIDDK NIH HHS P30 DK034854NIGMS NIH HHS R01 GM143277
6 · The paper itself

Abstract

Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hindered by the massive density of bacterial mRNA. To overcome this challenge, we combine 1000-fold volumetric expansion with multiplexed error robust fluorescence

Identifiers

PMID38979245
PMCPMC11230453

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.