Evidence map›Paper›PMID 38979223›Full record

ArticlebioRxiv : the preprint server for biology2025

Cell type-specific inhibitory modulation of sound processing in the auditory thalamus.

S Rolón-Martínez, A J Mendoza, C F Angeloni, N W Vogler, R Chen, K Vu, J S Haas, M N Geffen

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

S Rolón-MartínezDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, United States.
A J MendozaDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
C F AngeloniDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, United States.
N W VoglerDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, United States.
R ChenDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, United States.
K VuDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
J S HaasDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
M N GeffenDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, United States.ORCID 0000-0003-3022-2993

Funding

Circuit Mechanisms of Sound Processing and Detection in the Auditory PathwayR01DC014479 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI GEFFEN, MARIA NEIMARK · 2015 to 2024
$4.7M
Neuronal circuits supporting learning-driven changes in auditory perception.R01DC015527 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI Maria Neimark Geffen · 2017 to 2026
$4.5M
Neuronal circuits for context-driven bias in auditory categorizationR01NS113241 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI COHEN, YALE E, GEFFEN, MARIA NEIMARK · 2019 to 2023
$3.5M
Identifying Electrically Coupled Networks in vitroR01NS128713 · NINDS · LEHIGH UNIVERSITY · PI JULIE S HAAS · 2022 to 2026
$1.9M
The role of cortical interneurons in auditory processing and learningR03DC013660 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI GEFFEN, MARIA NEIMARK · 2013 to 2015
$480k
The function of cortical gain adaptation in detecting sounds in noise.F31DC016524 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI ANGELONI, CHRISTOPHER F. · 2017 to 2019
$123k
The function of thalamic inhibition in auditory processingF31DC018473 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI ROLON-MARTINEZ, SOLYMAR · 2020 to 2021
$79k
NIDCD NIH HHS F31 DC016524NIDCD NIH HHS F31 DC018473NIDCD NIH HHS R01 DC014479NIDCD NIH HHS R01 DC015527NIDCD NIH HHS R03 DC013660NINDS NIH HHS R01 NS113241NINDS NIH HHS R01 NS128713
6 · The paper itself

Abstract

Inhibition plays an important role in controlling the flow and processing of auditory information throughout the central auditory pathway, yet how inhibition shapes auditory processing in the medial geniculate body (MGB), the key region in the auditory thalamus, is poorly understood. MGB gates the flow of auditory information to the auditory cortex, and it is inhibited largely by the thalamic reticular nucleus (TRN). The TRN comprises two major classes of inhibitory neurons: parvalbumin (PV

Identifiers

PMID38979223
PMCPMC11230419

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.