Evidence map›Paper›PMID 38979202›Full record

ArticlebioRxiv : the preprint server for biology2024

An RNA interference approach for functional studies in the sea urchin and its use in analysis of Nodal signaling gradients.

Keen Wilson, Carl Manner, Esther Miranda, Alejandro Berrio, Gregory A Wray, David R McClay

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Keen WilsonDepartment of Biology, Duke University, Durham, NC USA.
Carl MannerDepartment of Biology, Duke University, Durham, NC USA.ORCID 0000-0003-3162-1478
Esther MirandaDepartment of Biology, Duke University, Durham, NC USA.
Alejandro BerrioDepartment of Biology, Duke University, Durham, NC USA.
Gregory A WrayDepartment of Biology, Duke University, Durham, NC USA.ORCID 0000-0001-5634-5081
David R McClayDepartment of Biology, Duke University, Durham, NC USA.

Funding

EMBRYONIC CELL RECOGNITION: SPECIFICTY DETERMINANTSR01HD014483 · NICHD · DUKE UNIVERSITY · PI DAVID MCCLAY · 1985 to 2026
$7.3M
NICHD NIH HHS R01 HD014483
6 · The paper itself

Abstract

Dicer substrate interfering RNAs (DsiRNAs) destroy targeted transcripts using the RNA-Induced Silencing Complex (RISC) through a process called RNA interference (RNAi). This process is ubiquitous among eukaryotes. Here we report the utility of DsiRNA in embryos of the sea urchin

Indexed as

developmentDorsal-ventralDsiRNALeftyNodalSea urchin

Identifiers

PMID38979202
PMCPMC11230266

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.