Evidence map›Paper›PMID 38979120›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2024

Natural Killer Cell Presence in Antibody-Mediated Rejection.

Matthias Diebold, Evan A Farkash, Jenna Barnes, Heinz Regele, Nicolas Kozakowski, Martina Schatzl, Katharina A Mayer, Susanne Haindl, Hannes Vietzen, Luis G Hidalgo and 3 more

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Dual inhibition of mTOR and calcineurin pathways mitigates missing self-induced NK cell-mediated microvascular rejection.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Antibody-mediated rejection-treatment standard.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  9. Article
  10. Article
  11. Targeting CD38 in Antibody-Mediated Rejection.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Matthias Diebold *Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Evan A Farkash *Department of Pathology, University of Michigan, Ann Arbor, MI, United States.
Jenna BarnesDepartment of Pathology, University of Michigan, Ann Arbor, MI, United States.
Heinz RegeleDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Nicolas KozakowskiDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Martina SchatzlDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Katharina A MayerDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Susanne HaindlDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Hannes VietzenCenter for Virology, Medical University of Vienna, Vienna, Austria.
Luis G HidalgoDepartment of Surgery, University of Wisconsin, Madison, WI, United States.
Philip F HalloranAlberta Transplant Applied Genomics Centre, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Farsad Eskandary *Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Georg A Böhmig *Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcript analyses highlight an important contribution of natural killer (NK) cells to microvascular inflammation (MVI) in antibody-mediated rejection (ABMR), but only few immunohistologic studies have quantified their spatial distribution within graft tissue. This study included 86 kidney transplant recipients who underwent allograft biopsies for a positive donor-specific antibody (DSA) result. NK cells were visualized and quantified within glomeruli and peritubular capillaries (PTC), using immunohistochemistry for CD34 alongside CD16/T-bet double-staining. Staining results were analyzed in relation to histomorphology, microarray analysis utilizing the Molecular Microscope Diagnostic System, functional NK cell genetics, and clinical outcomes. The number of NK cells in glomeruli per mm

Indexed as

Graft RejectionKidney TransplantationKiller Cells, NaturalAdultAgedBiopsyFemaleHumansImmunohistochemistryIsoantibodiesKidney GlomerulusMaleMiddle AgedReceptors, IgGIsoantibodiesReceptors, IgGantibody-mediated rejectiongeneticsimmunohistochemistrymicrovascular inflammationnatural killer cell

Identifiers

PMID38979120
PMCPMC11228143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.