Evidence map›Paper›PMID 38978879›Full record

ArticleCureus2024

The Association of Lower Levels of Baseline Proteinuria With Earlier Remission in Primary Membranous Nephropathy.

Jerry Joseph, Thirumavalavan Subramanian, Murugesan Vellaisamy, Srinivasaprasad Nd, Sujith Surendran, Thirumalvalavan Kaliaperumal, Poongodi Annadurai, Nived Haridas, Edwin Fernando

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jerry JosephNephrology, Government Stanley Medical College and Hospital, Chennai, IND.
Thirumavalavan SubramanianNephrology, Government Stanley Medical College and Hospital, Chennai, IND.
Murugesan VellaisamyNephrology, Government Stanley Medical College and Hospital, Chennai, IND.
Srinivasaprasad NdNephrology, Government Stanley Medical College and Hospital, Chennai, IND.
Sujith SurendranNephrology, Government Stanley Medical College and Hospital, Chennai, IND.
Thirumalvalavan KaliaperumalNephrology, Government Stanley Medical College and Hospital, Chennai, IND.
Poongodi AnnaduraiNephrology, Government Stanley Medical College and Hospital, Chennai, IND.
Nived HaridasNephrology, Government Stanley Medical College and Hospital, Chennai, IND.
Edwin FernandoNephrology, Government Stanley Medical College and Hospital, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim To study the clinical profile and course and to assess the outcome of patients with biopsy-proven primary membranous nephropathy (MN). Methods This study was carried out in a tertiary care hospital between December 2017 and December 2021 on four-year retrospective biopsy-proven patients with membranous nephropathy (MN). Urinary proteins, serum albumin, and serum creatinine were the baseline investigations that were performed. Special tests were done whenever necessary. Patients were treated with a modified Ponticelli (MP) regimen whenever needed. Patients were followed up after treatment administration for a minimum of a year. Results The study was done in 48 biopsy-proven MN patients. Thirty-six patients had primary MN with a mean age of 47+/-11.7 years. The male-female ratio was 2.6:1. Hypertension was present in 39% (14 patients), microscopic hematuria in 28% (10 patients), and acute kidney injury in 22% (8 patients). The mean 24-hour urinary protein was 11.2+/-2.9 g/day. PLA2R was positive in 78% (28 patients) of primary MN patients. Spontaneous remission was noted in 13.8% (5 patients) who were treated conservatively. Spontaneous remission was associated with lower baseline proteinuria (p<0.001), higher baseline serum albumin (p

Indexed as

membranous nephropathynephrotic syndromepla2rprimary membranous nephropathysecondary membranous nephropathy

Identifiers

PMID38978879
PMCPMC11230608

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.