Evidence map›Paper›PMID 38978741›Full record

ArticleFrontiers in oncology2024

Real-world evaluation of health-related quality of life in patients with diffuse large B-cell lymphoma based on a multinational survey.

P Connor Johnson, Abigail Bailey, Qiufei Ma, Neil Milloy, Jake Butcher, Isaac Sanderson, Sarah Weatherby, Rachael Meadows, Ruben G W Quek

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

P Connor JohnsonCancer Center, Massachusetts General Hospital, Boston, MA, United States.
Abigail BaileyAdelphi Real World, Bollington, United Kingdom.
Qiufei MaHealth Economics and Outcomes Research, Regeneron Pharmaceuticals Inc., Tarrytown, NY, United States.
Neil MilloyAdelphi Real World, Bollington, United Kingdom.
Jake ButcherAdelphi Real World, Bollington, United Kingdom.
Isaac SandersonAdelphi Real World, Bollington, United Kingdom.
Sarah WeatherbyAdelphi Real World, Bollington, United Kingdom.
Rachael MeadowsAdelphi Real World, Bollington, United Kingdom.
Ruben G W QuekHealth Economics and Outcomes Research, Regeneron Pharmaceuticals Inc., Tarrytown, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Real-world health-related quality of life (HRQoL) data in patients with diffuse large B-cell lymphoma (DLBCL) are scarce. This study is to compare patient-reported outcomes in patients with DLBCL across therapy lines and countries. Methods: Data were derived from the Adelphi DLBCL Disease Specific Programme™ from January 2021 to May 2021, a survey of physicians and their DLBCL patients in France, Germany, Italy, Spain, United Kingdom (UK), and the United States (US). Results: Overall, analysis was conducted on 441 patients with DLBCL across Europe and the US (mean age 64.6 years, 64% male); 68% had an Ann Arbor stage III and 69% had an Eastern Cooperative Oncology Group Performance Status of 0 to 1. The mean overall GHS/QoL was 54.1; patients on their 3L+ therapy had a lower mean GHS/QoL compared with patients on 1L/2L ( Conclusion: Patient-reported outcomes of DLBCL patients remain poor and patients continue to experience considerable morbidity.

Indexed as

cross-sectional studydiffuse large B-cell lymphomadisease burdenpatient reported outcome measuresquality of life

Identifiers

PMID38978741
PMCPMC11228594

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.