Evidence map›Paper›PMID 38978638›Full record

ArticleHemaSphere2024

Childhood myelodysplastic syndromes: Is cytoreductive therapy useful before allogeneic hematopoietic stem cell transplantation?

Baptiste Le Calvez, Maxime Jullien, Jean H Dalle, Cécile Renard, Charlotte Jubert, Arthur Sterin, Catherine Paillard, Anne Huynh, Sarah Guenounou, Bénédicte Bruno and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HemaSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Baptiste Le CalvezDepartment of Pediatric Hematology CHU Hôtel Dieu Nantes France.ORCID 0000-0001-5148-3792
Maxime JullienDepartment of Clinical Hematology CHU Hôtel Dieu Nantes France.
Jean H DalleDepartment of Pediatric Hematology, Robert Debré Hospital GHU APHPNOrd-Université Paris Cité Paris France.
Cécile RenardDepartment of Pediatric Hematology IHOPe, HCL Lyon Lyon France.
Charlotte JubertDepartment of Pediatric Hematology Oncology F-33000 Bordeaux Bordeaux France.
Arthur SterinDepartment of Pediatric Hematology La Timone APHM, Marseille France.
Catherine PaillardDepartment of Pediatric Hematology Strasbourg France.
Anne HuynhDepartment of Hematology CHU/IUCT Oncopole Toulouse Toulouse France.
Sarah GuenounouDepartment of Hematology CHU/IUCT Oncopole Toulouse Toulouse France.
Bénédicte BrunoDepartment of Pediatric Hematology Hôpital Jeanne de Flandre, CHRU Lille Lille France.
Virginie GandemerDepartment of Pediatric OncoHematology Rennes University Hospital, University of Rennes Rennes France.
Nimrod BuchbinderDepartment of Pediatric Hematology Hopital Charles Nicolle CHU Rouen Tunis Tunisia.
Pauline SimonDepartment of Pediatric Hematology CHRU de Besancon Besancon France.
Cécile PochonDepartment of Pediatric Hematology CHRU de Nancy Nancy France.
Anne SirventDepartment of Pediatric Hematology CHU de Montpellier Montpellier France.
Dominique PlantazDepartment of Pediatric Hematology CHU Grenoble Alpes Grenoble La Tronche France.
Justyna KanoldDepartment of Pediatric Hematology CHU de Clermont Ferrand Clermont-Ferrand France.
Marie C BénéCRCI2NA, INSERM U1307, CNRS Université d'Angers/Université de Nantes France.
Fanny RiallandDepartment of Pediatric Hematology CHU Hôtel Dieu Nantes France.
Audrey GrainDepartment of Pediatric Hematology CHU Hôtel Dieu Nantes France.
Société Francophone de Greffe de Moelle et de Thérapie Cellulaire (SFGM‐TC)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For most patients with childhood myelodysplastic syndrome (cMDS), allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the only curative option. In the case of increased blasts (cMDS-IB), the benefit of pretransplant cytoreductive therapy remains controversial. In this multicenter retrospective study, the outcomes of all French children who underwent allo-HSCT for cMDS reported in the SFGM-TC registry between 2000 and 2020 were analyzed (

Identifiers

PMID38978638
PMCPMC11229429

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.