Evidence map›Paper›PMID 38978637›Full record

ArticleHemaSphere2024

Infections in patients with mantle cell lymphoma.

Kossi D Abalo, Sara Ekberg, Therese M L Andersson, Simon Pahnke, Alexandra Albertsson-Lindblad, Karin E Smedby, Mats Jerkeman, Ingrid Glimelius

Abstract read
In one paragraph

Article in HemaSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kossi D AbaloDepartment of Immunology, Genetics and Pathology, Cancer Precision Medicine Uppsala University Uppsala Sweden.ORCID 0000-0001-5064-0215
Sara EkbergDepartment of Immunology, Genetics and Pathology, Cancer Precision Medicine Uppsala University Uppsala Sweden.
Therese M L AnderssonDepartment of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden.
Simon PahnkeDepartment of Immunology, Genetics and Pathology, Cancer Precision Medicine Uppsala University Uppsala Sweden.
Alexandra Albertsson-LindbladDivision of Oncology, Department of Clinical Sciences Lund, Skåne University Hospital Lund University Lund Sweden.ORCID 0000-0001-6273-8594
Karin E SmedbyDepartment of Medicine Solna, Clinical Epidemiology Division Karolinska Institutet Stockholm Sweden.
Mats JerkemanDivision of Oncology, Department of Clinical Sciences Lund, Skåne University Hospital Lund University Lund Sweden.
Ingrid GlimeliusDepartment of Immunology, Genetics and Pathology, Cancer Precision Medicine Uppsala University Uppsala Sweden.ORCID 0000-0001-6158-3041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancements in treatments have significantly improved the prognosis for mantle cell lymphoma (MCL), and there is a growing population of survivors with an increased susceptibility to infections. We assessed the incidence of infections by clinical characteristics and treatment both before and after MCL diagnosis in Sweden. Patients with a diagnosis of MCL ≥ 18 years between 2007 and 2019 were included, along with up to 10 matched comparators. Infectious disease diagnosis and anti-infective drug dispensation were identified by the National Patient and the Prescribed Drug Registers, respectively. Patients and comparators were followed from the diagnosis/matching date until death, emigration, or June 30, 2020. Overall, 1559 patients and 15,571 comparators were followed for a median duration of 2.9 and 5 years, respectively. The infection rate among patients was twofold higher, RRadj = 2.14 (2.01-2.27), contrasted to the comparator group. There was a notable rise in infection rates already 4 years before MCL diagnosis, which reached a fourfold increase in the first year after diagnosis and persisted significantly increased for an additional 8 years. Among patients, 69% (

Identifiers

PMID38978637
PMCPMC11228544

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.