Evidence map›Paper›PMID 38978598›Full record

ArticleResearch square2024

Patch and matrix striatonigral neurons differentially regulate locomotion.

Huaibin Cai, Jie Dong, Lupeng Wang, Breanna Sullivan, Lixin Sun, Lisa Chang, Victor Martinez Smith, Jinhui Ding, Weidong Le, Charles Gerfen

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Huaibin CaiNational Institutes of Health.ORCID 0000-0002-8596-6108
Jie DongNational Institutes of Health.
Lupeng WangNational Institutes of Health.
Breanna SullivanNational Institutes of Health.ORCID 0000-0002-8597-2276
Lixin SunNational Institute on Aging, National Institutes of Health.
Lisa ChangNational Institute on Aging, National Institutes of Health.
Victor Martinez SmithNational Institutes of Health.ORCID 0009-0005-6826-4226
Jinhui DingNational Institute on Aging, National Institutes of Health.
Weidong LeDalian Medical University.ORCID 0000-0001-7459-2705
Charles GerfenNIH.ORCID 0000-0001-9008-4882

Funding

Molecular and Pathophysiological Study of Parkinson's DiseaseZIAAG000928 · NIA · NATIONAL INSTITUTE ON AGING · PI CAI, HUAIBIN · 2011 to 2025
$15.8M
The Function and Pathogenic Mechanisms of LRRK2/Dardarin in Parkinson's DiseaseZIAAG000944 · NIA · NATIONAL INSTITUTE ON AGING · PI CAI, HUAIBIN · 2009 to 2025
$10.2M
The Function and Pathogenic Mechanisms of LRRK2/Dardarin in Parkinson's DiseaseZ01AG000944 · NIA · NATIONAL INSTITUTE ON AGING · PI CAI, HUAIBIN · 2008 to 2008
$499k
Intramural NIH HHS Z01 AG000944Intramural NIH HHS ZIA AG000944
6 · The paper itself

Abstract

The striatonigral neurons are known to promote locomotion

Indexed as

aldehyde dehydrogenase 1a1 (ALDH1A1)dopaminedorsal striatumGABA-B receptor (Gabbr1)Kremen1locomotionmatrix and patch compartmentsnigrostriatal dopaminergic neuronsspiny projection neuronstriosomesubstantia nigra

Identifiers

PMID38978598
PMCPMC11230471

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.