Evidence map›Paper›PMID 38978571›Full record

ArticleResearch square2024

Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles.

Aidan Flynn, Andrew D Pattison, Shiva Balachander, Emma Boehm, Blake Bowen, Trisha Dwight, Fernando Rosello, Oliver Hofmann, Luciano Martelotto, Maia Zethoven and 24 more

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors.

Aidan FlynnCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.
Andrew D PattisonCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.
Shiva BalachanderCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.
Emma BoehmCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.
Blake BowenCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.
Trisha DwightKolling Institute of Medical Research, Royal North Shore Hospital St Leonards NSW, Australia.
Fernando RoselloPeter MacCallum Cancer Centre, Melbourne, Australia.
Oliver HofmannCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.
Luciano MartelottoCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.ORCID 0000-0002-9625-1183
Maia ZethovenPeter MacCallum Cancer Centre, Melbourne, Australia.
Lawrence S KirschnerDivision of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
Tobias ElseUniversity of Michigan, Ann Arbor, MI, USA.
Lauren FishbeinDepartment of Medicine, Division of Endocrinology, Metabolism, Diabetes, University of Colorado, Aurora, CO, USA.
Anthony J GillSydney Medical School, University of Sydney, Sydney NSW, Australia.
Arthur S TischlerTufts Medical Centre, Boston, MA, USA.
Thomas GiordanoUniversity of Michigan, Ann Arbor, MI, USA.
Tamara ProdanovEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
Jane R NobleChildren's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.
Roger R ReddelChildren's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.ORCID 0000-0002-6302-6107
Alison H TrainerPeter MacCallum Cancer Centre, Melbourne, Australia.
Hans Kumar GhayeeUniversity of Florida and Malcom Randall VA Medical Center, Gainesville, FL, USA.
Isabelle BourdeauCentre hospitalier de l'université de Montréal, Montreal, Canada.
Marianne ElstonWaikato Clinical Campus, University of Auckland, Hamilton, New Zealand.
Diana IshakNational Cancer Centre, Singapore.
Joanne Ngeow Yuen YieNational Cancer Centre, Singapore.
Rodney J HicksSt Vincent's Dept of Medicine, University of Melbourne, VIC, Australia.
Joakim Crona18a Department of Medical Sciences, 18b Department of Surgical Sciences, Uppsala University, Sweden.ORCID 0000-0003-0677-4894
Tobias Åkerström18a Department of Medical Sciences, 18b Department of Surgical Sciences, Uppsala University, Sweden.
Peter Stålberg18a Department of Medical Sciences, 18b Department of Surgical Sciences, Uppsala University, Sweden.ORCID 0000-0002-9625-1394
Patricia DahiaDiv. Hematology and Medical Oncology, Department of Medicine, Mays Cancer Center, University of Texas Health Science Center at San Antonio (UTHSCSA), TX, USA.ORCID 0000-0002-7757-370X
Sean GrimmondCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.ORCID 0000-0002-8102-7998
Roderick Clifton-BlighKolling Institute of Medical Research, Royal North Shore Hospital St Leonards NSW, Australia.ORCID 0000-0002-1545-0368
Karel PacakEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.ORCID 0000-0002-3541-3767
Richard W TothillCentre for Cancer Research and Department of Clinical Pathology, University of Melbourne, VIC, Australia.ORCID 0000-0003-4522-1184

Funding

Evaluating the impact of genetic ancestry on the biology and drug response profile of pheochromocytoma and paraganglioma-derived organoid modelsR01CA264248 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DAHIA, PATRICIA LEAL, SORAGNI, ALICE · 2021 to 2025
$3.2M
Interaction of the TMEM127 tumor suppressor with the mTORC1 lysosomal activating complexR01GM114102 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DAHIA, PATRICIA LEAL · 2017 to 2021
$1.5M
NCI NIH HHS R01 CA264248NIGMS NIH HHS R01 GM114102
6 · The paper itself

Abstract

Hereditary

Identifiers

PMID38978571
PMCPMC11230496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.