Evidence map›Paper›PMID 38978538›Full record

ReviewBiomedical reports2024

Bone mineral density in osseointegration implant surgery: A review of current studies (Review).

Joshua C Carr, Sai Pranitha Pedagandham, Amelia Giugni, Christina Shen, Alice M Kim, Elise M Cribbin, Xiaoqi Lin, Atiya Oomatia, William Lu, Munjed Al Muderis and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomedical reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joshua C CarrKolling Institute, Faculty of Medicine and Health, University of Sydney, St Leonards, NSW 2065, Australia.
Sai Pranitha PedagandhamSchool of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Amelia GiugniSchool of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Christina ShenOsseointegration Group of Australia, Sydney, NSW 2153, Australia.
Alice M KimSchool of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Elise M CribbinSchool of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Xiaoqi LinSchool of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Atiya OomatiaOsseointegration Group of Australia, Sydney, NSW 2153, Australia.
William LuOsseointegration Group of Australia, Sydney, NSW 2153, Australia.
Munjed Al MuderisOsseointegration Group of Australia, Sydney, NSW 2153, Australia.
Dan XingArthritis Clinic and Research Center, Peking University People's Hospital, Peking University, Beijing 100044, P.R. China.
Jiao Jiao LiKolling Institute, Faculty of Medicine and Health, University of Sydney, St Leonards, NSW 2065, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osseointegration implant (OI) surgery is the latest rehabilitation technology for amputees, where a bone-anchored implant obviates the limitations of traditional socket prostheses. The bone mineral density (BMD) in the periprosthetic and other anatomical regions can be used to assess bone remodelling following OI surgery. Currently, limited studies have used BMD measurements in reporting post-operative OI outcomes and the association between the maintenance of BMD and implant efficacy has remained elusive. This review captured and analysed all studies that have reported the BMD as an objective outcome measure in patients with trans-femoral or trans-tibial OI. The PubMed, Medline, Scopus and Web of Science databases were searched using the terms 'amputation', 'osseointegration' and 'bone mineral density'. A total of 6 studies involving human participants were included for analysis. All studies used dual X-ray absorptiometry and/or X-rays for measuring BMD. Rehabilitation of trans-femoral or trans-tibial amputation using OI may help restore healthy BMD by enabling physiological bone loading. However, there is a low correlation between the BMD around the OI and the success of OI surgery or the risk of periprosthetic fractures. This review summarises the current evidence on BMD assessment in OI for lower limb amputee rehabilitation. Despite the great variability in the results, the available evidence suggests that OI may help restore BMD following surgery. The limited evidence calls for further investigation, as well as the development of a standard BMD measurement protocol.

Indexed as

amputationbone mineral densityimplantsosseointegration

Identifiers

PMID38978538
PMCPMC11229397

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.