Proton Transfer via Arginine with Suppressed p

Qian Wang, Aleksey Aleshintsev, Kamal Rai, Eric Jin, Rupal Gupta

Abstract read

In one paragraph

Article in The journal of physical chemistry. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qian WangDepartment of Chemistry, College of Staten Island, City University of New York, Staten Island, New York 10314, United States.

Aleksey AleshintsevDepartment of Chemistry, College of Staten Island, City University of New York, Staten Island, New York 10314, United States.

Kamal RaiDepartment of Chemistry, College of Staten Island, City University of New York, Staten Island, New York 10314, United States.

Eric JinStaten Island Technical High School, Staten Island, New York 10306, United States.

Rupal GuptaDepartment of Chemistry, College of Staten Island, City University of New York, Staten Island, New York 10314, United States.ORCID 0000-0001-8637-6129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gentisate and salicylate 1,2-dioxygenases (GDO and SDO) facilitate aerobic degradation of aromatic rings by inserting both atoms of dioxygen into their substrates, thereby participating in global carbon cycling. The role of acid-base catalysts in the reaction cycles of these enzymes is debatable. We present evidence of the participation of a proton shuffler during catalysis by GDO and SDO. The pH dependence of Michaelis-Menten parameters demonstrates that a single proton transfer is mandatory for the catalysis. Measurements at variable temperatures and pHs were used to determine the standard enthalpy of ionization (Δ

Indexed as

ArginineProtonsBiocatalysisCatalysisDioxygenasesGentisatesHydrogen-Ion ConcentrationThermodynamicsArginineDioxygenasesGentisatesProtonssalicylate 1,2-dioxygenase, Pseudaminobacter salicylatoxidans

Identifiers

PMID38978492

DOI10.1021/acs.jpcb.4c03164

PMCPMC11264262

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.