Evidence map›Paper›PMID 38978218›Full record

ArticleInvestigative and clinical urology2024

Korean urobiome platform (KUROM) study for acute uncomplicated sporadic versus recurrent cystitis in women: Clinical significance.

Jeong-Ju Yoo, Hee Bong Shin, Ji Eun Moon, Sul Hee Lee, Hyemin Jeong, Hee Jo Yang, Woong Bin Kim, Kwang Woo Lee, Jae Heon Kim, Young Ho Kim

Abstract readComparative Study
In one paragraph

Article in Investigative and clinical urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. More than an infection: the ecological puzzle of recurrent urinary tract infections.Frontiers in cellular and infection microbiology · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeong-Ju Yoo *Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.ORCID 0000-0002-7802-0381
Hee Bong Shin *Department of Laboratory Medicine and Genetics, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.ORCID 0000-0001-5602-5723
Ji Eun MoonDepartment of Statistics, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.ORCID 0000-0002-0887-703X
Sul Hee LeeDepartment of Dermatology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.ORCID 0000-0002-2990-9774
Hyemin JeongDepartment of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.ORCID 0000-0001-6227-681X
Hee Jo YangDepartment of Urology, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.ORCID 0000-0002-7195-806X
Woong Bin KimDepartment of Urology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.ORCID 0000-0002-7369-490X
Kwang Woo LeeDepartment of Urology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.ORCID 0000-0002-8882-2492
Jae Heon KimDepartment of Urology, Soonchunhyang University Seoul Hospital, Seoul, Korea.ORCID 0000-0002-4490-3610
Young Ho KimDepartment of Urology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. yhkuro@schmc.ac.kr.ORCID 0000-0003-3959-0928

Funding

NRF 2021R1G1A1007886NRF 2021R1G1A1010833SCH
6 · The paper itself

Abstract

purposeTo investigate urine microbiome differences among healthy women, women with recurrent uncomplicated cystitis (rUC), and those with sporadic/single uncomplicated cystitis (sUC) to challenge traditional beliefs about origins of these infections. MATERIALS AND

methodsPatients who underwent both conventional urine culture and next-generation sequencing (NGS) of urine were retrospectively reviewed. Symptom-free women with normal urinalysis results as a control group were also studied. Samples were collected via transurethral catheterization.

resultsIn the control group, urine microbiome was detected on NGS in 83.3%, with

conclusionsUrine microbiomes in control, sUC, and rUTI/rUC groups exhibited distinct characteristics. Notably, sUC and rUC might represent entirely separate pathological processes, given their distinct urine microbiomes. Consequently, the use of urine NGS might be essential to enhancing sensitivity compared to conventional urine culture in both sUC and rUTI/rUC groups.

Indexed as

CystitisMicrobiotaRecurrenceAcute DiseaseAdultAgedClinical RelevanceFemaleHigh-Throughput Nucleotide SequencingHumansMiddle AgedRepublic of KoreaRetrospective StudiesUrinary Tract InfectionsUrine16S rRNA next-generation sequencingCystitisMicrobiomeUrinary tract infections

Identifiers

PMID38978218
PMCPMC11231657

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.