Evidence map›Paper›PMID 38978144›Full record

ReviewMilitary Medical Research2024

Crisis in the gut: navigating gastrointestinal challenges in Gulf War Illness with bioengineering.

Claudia A Collier, Aelita Salikhova, Sufiyan Sabir, Steven Foncerrada, Shreya A Raghavan

Abstract readReview
In one paragraph

Review in Military Medical Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claudia A CollierDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA.ORCID 0000-0002-3440-2863
Aelita SalikhovaDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA.
Sufiyan SabirDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA.
Steven FoncerradaDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA.
Shreya A RaghavanDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA. sraghavan@tamu.edu.

Funding

Congressionally Directed Medical Research Programs W81XWH-21-1-0477
6 · The paper itself

Abstract

Gulf War Illness (GWI) is characterized by a wide range of symptoms that manifests largely as gastrointestinal symptoms. Among these gastrointestinal symptoms, motility disorders are highly prevalent, presenting as chronic constipation, stomach pain, indigestion, diarrhea, and other conditions that severely impact the quality of life of GWI veterans. However, despite a high prevalence of gastrointestinal impairments among these veterans, most research attention has focused on neurological disturbances. This perspective provides a comprehensive overview of current in vivo research advancements elucidating the underlying mechanisms contributing to gastrointestinal disorders in GWI. Generally, these in vivo and in vitro models propose that neuroinflammation alters gut motility and drives the gastrointestinal symptoms reported in GWI. Additionally, this perspective highlights the potential and challenges of in vitro bioengineering models, which could be a crucial contributor to understanding and treating the pathology of gastrointestinal related-GWI.

Indexed as

BioengineeringGastrointestinal DiseasesPersian Gulf SyndromeGastrointestinal TractHumansBioengineeringGastrointestinal motilityGulf War IllnessNeuroimmune crosstalk

Identifiers

PMID38978144
PMCPMC11229309

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.