Evidence map›Paper›PMID 38978086›Full record

ArticleParasites & vectors2024

The origin and insecticide resistance of Aedes albopictus mosquitoes established in southern Mozambique.

Sarina Yamashita, Kawane Uruma, Chao Yang, Yukiko Higa, Noboru Minakawa, Nelson Cuamba, Kyoko Futami

Abstract read
In one paragraph

Article in Parasites & vectors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarina YamashitaSchool of Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
Kawane UrumaSchool of Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
Chao YangDepartment of Medical Entomology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinkuku-Ku, Tokyo, 162-8640, Japan.
Yukiko HigaDepartment of Medical Entomology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinkuku-Ku, Tokyo, 162-8640, Japan.
Noboru MinakawaDepartment of Vector Ecology & Environment, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
Nelson CuambaInstituto Nacional de Saúde, Ministério da Saúde, C.P. 264, Maputo, Mozambique.
Kyoko FutamiDepartment of Vector Ecology & Environment, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan. futami@nagasaki-u.ac.jp.

Funding

Japan Agency for Medical Research and Development (AMED) JP15fm0108001
6 · The paper itself

Abstract

backgroundThe Aedes albopictus mosquito is of medical concern due to its ability to transmit viral diseases, such as dengue and chikungunya. Aedes albopictus originated in Asia and is now present on all continents, with the exception of Antarctica. In Mozambique, Ae. albopictus was first reported in 2015 within the capital city of Maputo, and by 2019, it had become established in the surrounding area. It was suspected that the mosquito population originated in Madagascar or islands of the Western Indian Ocean (IWIO). The aim of this study was to determine its origin. Given the risk of spreading insecticide resistance, we also examined relevant mutations in the voltage-sensitive sodium channel (VSSC).

methodsEggs of Ae. albopictus were collected in Matola-Rio, a municipality adjacent to Maputo, and reared to adults in the laboratory. Cytochrome c oxidase subunit I (COI) sequences and microsatellite loci were analyzed to estimate origins. The presence of knockdown resistance (kdr) mutations within domain II and III of the VSSC were examined using Sanger sequencing.

resultsThe COI network analysis denied the hypothesis that the Ae. albopictus population originated in Madagascar or IWIO; rather both the COI network and microsatellites analyses showed that the population was genetically similar to those in continental Southeast Asia and Hangzhou, China. Sanger sequencing determined the presence of the F1534C knockdown mutation, which is widely distributed among Asian populations, with a high allele frequency (46%).

conclusionsThese results do not support the hypothesis that the Mozambique Ae. albopictus population originated in Madagascar or IWIO. Instead, they suggest that the origin is continental Southeast Asia or a coastal town in China.

Indexed as

AedesInsecticide ResistanceMosquito VectorsAnimalsElectron Transport Complex IVFemaleInsecticidesMadagascarMicrosatellite RepeatsMozambiqueMutationVoltage-Gated Sodium ChannelsElectron Transport Complex IVInsecticidesVoltage-Gated Sodium ChannelsAedes albopictusCOIInvasionkdr mutationMicrosatellitesMozambique

Identifiers

PMID38978086
PMCPMC11229193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.