SynthesisCritical care (London, England)2024
Diagnostic accuracy of lung ultrasound in diagnosis of ARDS and identification of focal or non-focal ARDS subphenotypes: a systematic review and meta-analysis.
Synthesis in Critical care (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Accuracy of lung ultrasound in the diagnosis of acute respiratory distress syndrome: a systematic review and meta-analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Article
- Comparison of predictive values of Acute Physiology and Chronic Health Evaluation scores for mortality in sepsis: a systematic review and meta-analysis.World journal of emergency medicine · 2026Review
- Lung Imaging in Acute Hypoxemic Respiratory Failure: From Physics to Bedside Applications.Journal of clinical medicine · 2026Review
- Morphological subphenotypes in acute pancreatitis-related ARDS: limitations, extensions, and research priorities.Critical care (London, England) · 2026Article
- Measuring and managing pulmonary edema in ARDS: a narrative review.Critical care (London, England) · 2026Review
- Current Insights into Clinical, Molecular, and Therapeutic Approaches to Acute Respiratory Distress Syndrome.Medical sciences (Basel, Switzerland) · 2026Review
- [Anatomy of the Forest Plot graphic].Revista medica del Instituto Mexicano del Seguro Social · 2026Review
- Pneumonia detection from enhanced chest X-Ray images based on Double SGAN model.Scientific reports · 2026Article
- Multimodal phenotyping of ARDS: design and preliminary insights from the prospective BIOWARE cohort for precision critical management.Respiratory research · 2026Article
- Physiology-guided personalized mechanical ventilation to prevent ventilator-induced lung injury.Frontiers in medicine · 2026Review
- Personalized mechanical ventilation guided by lung ultrasound in patients with ARDS: a pilot phase of a randomized clinical trial.Intensive care medicine experimental · 2025Article
- Development and validation of a predictive model for postoperative acute respiratory distress syndrome in patients with type A aortic dissection based on the 2023 updated definition.Respiratory research · 2025Article
- Advances in bedside imaging: lung ultrasound.Intensive care medicine experimental · 2025Review
- Old and New Definitions of Acute Respiratory Distress Syndrome (ARDS): An Overview of Practical Considerations and Clinical Implications.Diagnostics (Basel, Switzerland) · 2025Review
- Imaging and pulmonary function techniques in ARDS diagnosis and management: current insights and challenges.Critical care (London, England) · 2025Review
- Connective Tissue Disorder-Induced Diffuse Alveolar Hemorrhage: A Comprehensive Review with an Emphasis on Airway and Respiratory Management.Life (Basel, Switzerland) · 2025Review
- Lung Ultrasound After COVID-19: A Pivotal Moment for Clinical Integration-Navigating Challenges and Seizing Opportunities.Healthcare (Basel, Switzerland) · 2025Review
- Lung ultrasound outperforms symptom-based screening to detect interstitial lung disease associated with rheumatoid arthritis.RMD open · 2025Article
- Lung injury in myocardial infarction-associated cardiogenic shock supported by venoarterial extracorporeal membrane oxygenation: a scoping review.BMC cardiovascular disorders · 2025Article
- Correlation of sonographic and radiographic scores of lung edema and metrics of shunt, dead space, and respiratory mechanics in invasively ventilated patients.Critical care science · 2025Observational
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute respiratory distress syndrome (ARDS) is a life-threatening respiratory condition with high mortality rates, accounting for 10% of all intensive care unit admissions. Lung ultrasound (LUS) as diagnostic tool for acute respiratory failure has garnered widespread recognition and was recently incorporated into the updated definitions of ARDS. This raised the hypothesis that LUS is a reliable method for diagnosing ARDS.
objectivesWe aimed to establish the accuracy of LUS for ARDS diagnosis and classification of focal versus non-focal ARDS subphenotypes.
methodsThis systematic review and meta-analysis used a systematic search strategy, which was applied to PubMed, EMBASE and cochrane databases. Studies investigating the diagnostic accuracy of LUS compared to thoracic CT or chest radiography (CXR) in ARDS diagnosis or focal versus non-focal subphenotypes in adult patients were included. Quality of studies was evaluated using the QUADAS-2 tool. Statistical analyses were performed using "Mada" in Rstudio, version 4.0.3. Sensitivity and specificity with 95% confidence interval of each separate study were summarized in a Forest plot.
resultsThe search resulted in 2648 unique records. After selection, 11 reports were included, involving 2075 patients and 598 ARDS cases (29%). Nine studies reported on ARDS diagnosis and two reported on focal versus non-focal ARDS subphenotypes classification. Meta-analysis showed a pooled sensitivity of 0.631 (95% CI 0.450-0.782) and pooled specificity of 0.942 (95% CI 0.856-0.978) of LUS for ARDS diagnosis. In two studies, LUS could accurately differentiate between focal versus non-focal ARDS subphenotypes. Insufficient data was available to perform a meta-analysis.
conclusionThis review confirms the hypothesis that LUS is a reliable method for diagnosing ARDS in adult patients. For the classification of focal or non-focal subphenotypes, LUS showed promising results, but more research is needed.
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