Evidence map›Paper›PMID 38978051›Full record

ArticleJournal of neuroengineering and rehabilitation2024

Neural basis of lower-limb visual feedback therapy: an EEG study in healthy subjects.

Ahmed Adham, Ba Thien Le, Julien Bonnal, Hugo Bessaguet, Etienne Ojardias, Pascal Giraux, Pascal Auzou

Registry-linked trialAbstract read
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In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05743647 (Assessment of Brain Activation With Different Mirror Therapy Tasks - Contribution of EEG and fNIRS in Healthy Subjects.), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05743647 completednot on this map

Assessment of Brain Activation With Different Mirror Therapy Tasks - Contribution of EEG and fNIRS in Healthy Subjects.

TypeobservationalSponsorCentre Hospitalier Régional d'OrléansRan2023 to 2023Enrolled38ConditionsHealthyArmsObservation (OBS), Observation and imagination (OBS-IM), Observation and realization (OBS-REAL)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmed AdhamDepartment of Physical Rehabilitation, CHU of St Etienne, Saint-Étienne, France. ahmed.adham@chu-st-etienne.fr.
Ba Thien LeDepartment of Neurology, CHU of Orleans, Orleans, France.
Julien BonnalDepartment of Neurology, CHU of Orleans, Orleans, France.
Hugo BessaguetDepartment of Physical Rehabilitation, CHU of St Etienne, Saint-Étienne, France.
Etienne OjardiasDepartment of Physical Rehabilitation, CHU of St Etienne, Saint-Étienne, France.
Pascal GirauxDepartment of Physical Rehabilitation, CHU of St Etienne, Saint-Étienne, France.
Pascal AuzouDepartment of Neurology, CHU of Orleans, Orleans, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVideo-feedback observational therapy (VOT) is an intensive rehabilitation technique based on movement repetition and visualization that has shown benefits for motor rehabilitation of the upper and lower limbs. Despite an increase in recent literature on the neurophysiological effects of VOT in the upper limb, there is little knowledge about the cortical effects of visual feedback therapies when applied to the lower limbs. The aim of our study was to better understand the neurophysiological effects of VOT. Thus, we identified and compared the EEG biomarkers of healthy subjects undergoing lower limb VOT during three tasks: passive observation, observation and motor imagery, observation and motor execution.

methodsWe recruited 38 healthy volunteers and monitored their EEG activity while they performed a right ankle dorsiflexion task in the VOT. Three graded motor tasks associated with action observation were tested: action observation alone (O), motor imagery with action observation (OI), and motor execution synchronized with action observation (OM). The alpha and beta event-related desynchronization (ERD) and event-related synchronization (or beta rebound, ERS) rhythms were used as biomarkers of cortical activation and compared between conditions with a permutation test. Changes in connectivity during the task were computed with phase locking value (PLV).

resultsDuring the task, in the alpha band, the ERD was comparable between O and OI activities across the precentral, central and parietal electrodes. OM involved the same regions but had greater ERD over the central electrodes. In the beta band, there was a gradation of ERD intensity in O, OI and OM over central electrodes. After the task, the ERS changes were weak during the O task but were strong during the OI and OM (Cz) tasks, with no differences between OI and OM.

conclusionAlpha band ERD results demonstrated the recruitment of mirror neurons during lower limb VOT due to visual feedback. Beta band ERD reflects strong recruitment of the sensorimotor cortex evoked by motor imagery and action execution. These results also emphasize the need for an active motor task, either motor imagery or motor execution task during VOT, to elicit a post-task ERS, which is absent during passive observation. Trial Registration NCT05743647.

Indexed as

ElectroencephalographyFeedback, SensoryHealthy VolunteersLower ExtremityAdultAlpha RhythmFemaleHumansImaginationMalePsychomotor PerformanceYoung AdultEEGLower limbMirror neuron systemRehabilitationVideo feedback therapy

Identifiers

PMID38978051
PMCPMC11229246

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.