ArticleCommunications medicine2024
Global prevalence and correlates of mpox vaccine acceptance and uptake: a systematic review and meta-analysis.
Article in Communications medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 7 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Prevalence of mpox infection among men who have sex with men: a systematic review and meta-analysis.Infectious diseases of poverty · 2026Pooled it
- Examining Benchmarks of Sexual Recidivism Rates for Short, Moderate, and Long-Term Follow-Up Periods: A Meta-Analysis of Canadian and American Studies.Trauma, violence & abuse · 2026Pooled it
- Mpox vaccine acceptance and uptake in Africa: a systematic review and meta-analysis.BMC global and public health · 2026Pooled it
- Mpox vaccination uptake and acceptance in the Democratic Republic of Congo: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2026Pooled it
- Mpox vaccine acceptance and its predictors among people who have risky sexual practices: A systematic review and meta-analysis.Human vaccines & immunotherapeutics · 2025Pooled it
- MPOX outbreak in Africa: the urgent need for local manufacturing of the vaccine and decolonized health systems.BMC public health · 2025Pooled it
- Prevalence of Mpox vaccine acceptance and hesitancy among people living with HIV: a comprehensive systematic review and meta-analysis.AIDS research and therapy · 2025Pooled it
- Mapping Mpox vaccine hesitancy using an integrated machine learning and structural equation modeling approach.Scientific reports · 2026Article
- Spatiotemporal Transmission Characteristics of Global Monkeypox - Worldwide, January 2022-September 2025.China CDC weekly · 2026Article
- Mpox disease epidemiology, vaccine uptake and vaccination coverage in Australia 2022-2024: a descriptive study.EClinicalMedicine · 2026Article
- The 2024 Central African Republic monkeypox outbreak: implications for pediatric involvement and global health.Pediatric research · 2026Review
- Determinants of Mpox vaccine uptake and hesitancy among healthcare workers in Port Harcourt, Nigeria.BMC infectious diseases · 2026Article
- Public preferences and decision-making for mpox vaccination in the African region: a multinational discrete choice experiment.BMJ global health · 2026Article
- Battle won, war ongoing: A call for mpox vaccination in high-risk dermatologic cases.JAAD case reports · 2025Article
- Mpox in People Living with HIV: Clinical Challenges, Preventive Strategies and Public Health Implications.Viruses · 2025Review
- Vaccination uptake and associated factors among HIV pre-exposure prophylaxis (PrEP) users: insights from a retrospective cross-sectional study.BMC public health · 2025Article
- 'It was something that I let slip by the wayside': a qualitative study of challenges to equitable mpox vaccination in the UK outbreak response.BMC public health · 2025Article
- Determinants of mpox vaccination uptake among MSM during the 2022 outbreak: a single-centre retrospective study at Lyon University Hospital, France.BMC public health · 2025Article
- Vaccination strategies to achieve outbreak control for MPXV Clade I with a one-time mass campaign in sub-Saharan Africa: A scenario-based modelling study.PLoS medicine · 2025Article
- The Evolution of Monkeypox Vaccination Acceptance in Romania: A Comparative Analysis (2022-2025), Psychosocial Perceptions, and the Impact of Anti-Vaccination Rhetoric on Societal Security.Behavioral sciences (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVaccination has been recommended as one of the most potent ways of controlling the mpox (formerly, monkeypox) outbreak, particularly among high-risk groups. Here, we evaluated the prevalence of mpox vaccine acceptance and uptake globally.
methodsWe searched multiple databases for peer-reviewed studies published in English from May 2022 to 25th November 2023 that evaluated mpox vaccine acceptance and/or uptake. We fit a random-effects model meta-analysis to calculate the pooled mpox vaccine acceptance and uptake rates, with their 95% confidence intervals (CI) across population outcomes. We performed subgroup analyses among the six World Health Organization (WHO) regions (Africa [AFR], Region of the Americas [AMR], South-East Asia Region [SEAR], European Region [EUR], Eastern Mediterranean Region [EMR], and the Western Pacific Region [WPR]), as well as among select population subgroups.
resultsOf the 2531 studies screened, 61 studies, with a cumulative sample size of 263,857 participants from 87 countries were eligible for inclusion. The overall vaccine acceptance and uptake rates were 59.7% and 30.9% globally. Acceptance and uptake rates among the LGBTQI+ community were 73.6% vs 39.8% globally, 60.9% vs. 37.1% in AMR, 80.9% vs. 50.0% in EUR, and 75.2% vs. 33.5% in WPR. Among PLHIV, vaccine acceptance and uptake rates were 66.4% vs. 35.7% globally, 64.0% vs. 33.9% in AMR, 65.1% vs. 27.0% in EUR, and 69.5% vs. 46.6% in WPR. Among healthcare workers, vaccination intention was 51.0% globally.
conclusionsTailored interventions are needed to bolster confidence in the mpox vaccine, maximize vaccine uptake, and increase vaccine access to close the gaps between acceptance and uptake especially among key populations residing in regions with low rates of acceptance and uptake.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.