Evidence map›Paper›PMID 38977497›Full record

ArticleSurgical endoscopy2024

Value of endoscopic grading of gastroesophageal flap valve in gastroesophageal reflux disease.

Wenjuan Wang, Quanyi Liu, Liya Luo, Jingjie Huang, Xia Hu, Zhengxiu Zhou, Xingchang Yang, Chunmei Chen, He Xia, Li Zhang and 10 more

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Wenjuan Wang *Department of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Quanyi Liu *Department of Cardiology, Xingyi People's Hospital, Xingyi, 562400, Guizhou Province, China.
Liya LuoDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Jingjie HuangDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Xia HuDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Zhengxiu ZhouDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Xingchang YangDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Chunmei ChenDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
He XiaDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Li ZhangDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Zhengqi YangDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Heliang LuDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Fang LiDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Mingjun CaiDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Zhihong LanDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Da ZhangDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Yuan ZhangDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Cui ZhangDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Chen GaoDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China.
Min WenDepartment of Gastroenterology, Xingyi People's Hospital, No 1 of Yingxiong Street, Xingyi, 562400, Guizhou Province, China. wenmin207@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the significance of endoscopic grading (Hill's classification) of gastroesophageal flap valve (GEFV) in the examination of patients with gastroesophageal reflux disease (GERD).

methodsOne hundred and sixty-two patients undergoing gastroscopy in the Department of Gastroenterology, Xingyi People's Hospital between Apr. 2022 and Sept. 2022 were selected by convenient sampling, and data such as GEFV grade, and findings of esophageal high-resolution manometry (HRM) and esophageal 24-h pH/impedance reflux monitoring, and Los Angeles (LA) classification of reflux esophagitis (RE) were collected and compared.

resultsStatistically significant differences in age (F = 9.711, P < 0.001) and hiatal hernia (χ = 35.729, P < 0.001) were observed in patients with different GEFV grades. The resting LES pressures were 12.12 ± 2.79, 10.73 ± 2.68, 9.70 ± 2.29, and 8.20 ± 2.77 mmHg (F = 4.571, P < 0.001) and LES lengths were 3.30 ± 0.70, 3.16 ± 0.68, 2.35 ± 0.83, and 2.45 ± 0.62 (F = 3.789, P = 0.011), respectively, in patients with GEFV grades I-IV. DeMeester score (Z = 5.452, P < 0.001), AET4 (Z = 5.614, P < 0.001), acid reflux score (upright) (Z = 7.452, P < 0.001), weak acid reflux score (upright) (Z = 3.121, P = 0.038), liquid reflux score (upright) (Z = 3.321, P = 0.031), acid reflux score (supine) (Z = 6.462, P < 0.001), mixed reflux score (supine) (Z = 3.324, P = 0.031), gas reflux score (supine) (Z = 3.521, P = 0.024) were different in patients with different GEFV grades, with statistically significant differences. Pearson correlation analysis revealed a positive correlation between RE grade and LA classification of GERD (r = 0.662, P < 0.001), and the severity of RE increased gradually with the increase of the Hill grades of GEFV.

conclusionThe Hill grade of GEFV is related to age, hiatal hernia, LES pressure, and the consequent development and severity of acid reflux and RE. Evaluation of esophageal motility and reflux based on the Hill grade of GEFV is of significance for the diagnosis and treatment of GERD.

Indexed as

Gastroesophageal RefluxManometryAdultAgedEsophageal pH MonitoringEsophageal Sphincter, LowerEsophagogastric JunctionFemaleGastroscopyHernia, HiatalHumansMaleMiddle AgedEsophageal 24-h pH/impedance monitoringGastroesophageal reflux diseaseHill gradesHRM

Identifiers

PMID38977497

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.