Evidence map›Paper›PMID 38977494›Full record

ArticleLung2024

Patient Perception of Cough in Interstitial Lung Disease; Impact of Cough Hypersensitivity.

B Hirons, K Rhatigan, L Wright, H Kesavan, E Mackay, P S P Cho, S S Birring, K J Myall

Abstract read
In one paragraph

Article in Lung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Cough and dyspnea management in pulmonary fibrosis.Current opinion in supportive and palliative care · 2025
    Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

B HironsDepartment of Respiratory Medicine, Chest Unit, Cheyne Wing, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.
K RhatiganDepartment of Respiratory Medicine, Chest Unit, Cheyne Wing, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.
L WrightAction for Pulmonary Fibrosis, Peterborough, UK.
H KesavanDepartment of Respiratory Medicine, Chest Unit, Cheyne Wing, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.
E MackayDepartment of Respiratory Medicine, Chest Unit, Cheyne Wing, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.
P S P ChoDepartment of Respiratory Medicine, Chest Unit, Cheyne Wing, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.
S S BirringDepartment of Respiratory Medicine, Chest Unit, Cheyne Wing, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.
K J MyallDepartment of Respiratory Medicine, Chest Unit, Cheyne Wing, King's College Hospital, Denmark Hill, London, SE5 9RS, UK. katherinejane.myall@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCough is common in interstitial lung disease (ILD) and is associated with disease progression, yet its mechanisms are understudied. We investigated cough hypersensitivity features and impact in ILD.

methodsParticipants with ILD and cough (n = 195) completed a multiple choice and free text questionnaire on cough sensations/triggers and impacts.

resultsThe majority of participants were male (54%), aged > 65 (64%), with idiopathic pulmonary fibrosis (IPF, 75%). Common cough triggers were body position (74%), physical activity (72%), and talking (62%). Common laryngeal sensations were globus (43%), and itch/tickle (42%). Cough impacted everyday life in 55%, and all activities in 31%, causing exhaustion (59%), social embarrassment (70%), urinary incontinence (46% females), and syncope/pre-syncope (12%). The total number of cough-provoking sensations/triggers correlated with impacts; ρ = 0.73, p < 0.001.

conclusionCough hypersensitivity symptoms are prevalent in ILD and detrimentally affect quality of life. Further studies investigating mechanisms of cough hypersensitivity and targeted pharmacotherapy are warranted.

Indexed as

CoughLung Diseases, InterstitialQuality of LifeActivities of Daily LivingAgedFemaleHumansIdiopathic Pulmonary FibrosisMaleMiddle AgedPerceptionSurveys and QuestionnairesSyncopeCough hypersensitivity syndromeImpactInterstitial lung diseaseQuality of life

Identifiers

PMID38977494
PMCPMC11272731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.