Evidence map›Paper›PMID 38977467›Full record

ArticleVirchows Archiv : an international journal of pathology2025

Müllerian clear cell carcinoma arising from rectal endometriosis with pericolonic lymph node metastasis.

Riley Lochner, John Nakayama, Emily Steinhagen, Christina Bagby, Min Cui

Erratum issuedAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Riley LochnerDepartment of Pathology, University Hospitals Cleveland Medical Center, Cleveland, USA.
John NakayamaDepartment of Gynecologic Oncology, Allegheny Health Network, Pittsburgh, USA.
Emily SteinhagenDepartment of Surgery, University Hospitals Cleveland Medical Center, Cleveland, USA.
Christina BagbyDepartment of Pathology, University Hospitals Cleveland Medical Center, Cleveland, USA.
Min CuiDepartment of Pathology, University Hospitals Cleveland Medical Center, Cleveland, USA. min.cui@uhhospitals.org.ORCID http://orcid.org/0000-0003-2445-1415

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of clear cell carcinoma arising in endometriosis of the rectum that provides insights to the biological behavior of this extremely rare tumor. The patient presented with a large rectal mass, and the biopsy was suggestive of clear cell carcinoma of Müllerian origin based on the morphology and immunoprofile. The patient underwent a proctosigmoidectomy and hysterectomy with bilateral salpingo-oophorectomy with clear cell carcinoma involving the colon. Five pericolonic lymph nodes were positive for carcinoma. Endometriosis was identified in the colonic wall adjacent to the carcinoma. No tumor was identified in the endometrium, fallopian tubes, or ovaries. ARID1A mutations were identified by next-generation sequencing. The patient underwent adjuvant chemotherapy and is disease-free 4 years after the diagnosis. To our knowledge, this is the first case of clear cell carcinoma arising in colon endometriosis with pericolonic lymph node metastasis.

Indexed as

Adenocarcinoma, Clear CellEndometriosisRectal NeoplasmsBiomarkers, TumorDNA-Binding ProteinsFemaleHumansLymphatic MetastasisLymph NodesMiddle AgedTranscription FactorsARID1A protein, humanBiomarkers, TumorDNA-Binding ProteinsTranscription Factors

Identifiers

PMID38977467

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.