Evidence map›Paper›PMID 38976793›Full record

ArticleOrganic letters2024

Telescoping a Prenyltransferase and a Diterpene Synthase to Transform Unnatural FPP Derivatives to Diterpenoids.

Henry Struwe, Heng Li, Finn Schrödter, Laurent Höft, Jörg Fohrer, Jeroen S Dickschat, Andreas Kirschning

Abstract read
In one paragraph

Article in Organic letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Henry StruweInstitute of Organic Chemistry, Leibniz University Hannover, Schneiderberg 1B, 30167 Hannover, Germany.
Heng LiKekulé-Institute of Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, 53121 Bonn, Germany.ORCID 0000-0002-6406-7269
Finn SchrödterInstitute of Organic Chemistry, Leibniz University Hannover, Schneiderberg 1B, 30167 Hannover, Germany.
Laurent HöftInstitute of Organic Chemistry, Leibniz University Hannover, Schneiderberg 1B, 30167 Hannover, Germany.
Jörg FohrerDepartment of Chemistry, Technical University Darmstadt, Alarich-Weiss-Straße 4, 64287 Darmstadt, Germany.
Jeroen S DickschatKekulé-Institute of Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, 53121 Bonn, Germany.ORCID 0000-0002-0102-0631
Andreas KirschningInstitute of Organic Chemistry, Leibniz University Hannover, Schneiderberg 1B, 30167 Hannover, Germany.ORCID 0000-0001-5431-6930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New diterpenoids are accessible from non-natural FPP derivatives as substrates for an enzymatic elongation cyclization cascade using the geranylgeranyl pyrophosphate synthase (GGPPS) from

Indexed as

Alkyl and Aryl TransferasesDimethylallyltranstransferaseDiterpenesStreptomycesBiotransformationCyclizationMolecular StructurePolyisoprenyl PhosphatesAlkyl and Aryl TransferasesDimethylallyltranstransferaseDiterpenesgeranylgeranyl pyrophosphatePolyisoprenyl Phosphatesterpene synthase

Identifiers

PMID38976793
PMCPMC11267608

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.