Evidence map›Paper›PMID 38976152›Full record

ArticleNeuroinformatics2024

Classifying Neuronal Cell Types Based on Shared Electrophysiological Information from Humans and Mice.

Ofek Ophir, Orit Shefi, Ofir Lindenbaum

Abstract read
In one paragraph

Article in Neuroinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. A Framework for Compressive On-Chip Action Potential Recording.IEEE transactions on bio-medical engineering · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ofek OphirFaculty of Engineering, Bar-Ilan University, Ramat-Gan, Israel.
Orit Shefi *Faculty of Engineering, Bar-Ilan University, Ramat-Gan, Israel. orit.shefi@biu.ac.il.
Ofir Lindenbaum *Faculty of Engineering, Bar-Ilan University, Ramat-Gan, Israel. ofir.lindenbaum@biu.ac.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain is an intricate system that controls a variety of functions. It consists of a vast number of cells that exhibit diverse characteristics. To understand brain function in health and disease, it is crucial to classify neurons accurately. Recent advancements in machine learning have provided a way to classify neurons based on their electrophysiological activity. This paper presents a deep-learning framework that classifies neurons solely on this basis. The framework uses data from the Allen Cell Types database, which contains a survey of biological features derived from single-cell recordings from mice and humans. The shared information from both sources is used to classify neurons into their broad types with the help of a joint model. An accurate domain-adaptive model, integrating electrophysiological data from both mice and humans, is implemented. Furthermore, data from mouse neurons, which also includes labels of transgenic mouse lines, is further classified into subtypes using an interpretable neural network model. The framework provides state-of-the-art results in terms of accuracy and precision while also providing explanations for the predictions.

Indexed as

Electrophysiological PhenomenaNeuronsAnimalsBrainDeep LearningHumansMachine LearningMiceMice, TransgenicNeural Networks, ComputerCell-type classificationDomain adaptationElectrophysiologyInterpretable neural networksNeuronal typesSparse neural networks

Identifiers

PMID38976152
PMCPMC11579117

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.