Evidence map›Paper›PMID 38976100›Full record

ArticleIntensive care medicine experimental2024

Impact of tracheostomy tube modalities on ventilatory mechanics: a bench study.

Yann Combret, Margaux Machefert, Guillaume Prieur, Emeline Fresnel, Elise Artaud-Macari, Bouchra Lamia, Marius Lebret, Clément Medrinal

Abstract read
In one paragraph

Article in Intensive care medicine experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yann CombretUniversité Paris-Saclay, UVSQ, Erphan, 78000, Versailles, France.
Margaux MachefertUniversité Paris-Saclay, UVSQ, Erphan, 78000, Versailles, France.
Guillaume PrieurUniversité Paris-Saclay, UVSQ, Erphan, 78000, Versailles, France.
Emeline FresnelKernel Biomedical, 18 Rue Marie Curie Bâtiment ANIDER, 76000, Rouen, France.
Elise Artaud-MacariUR3830 GRHVN, Institute for Research and Innovation in Biomedicine (IRIB), Normandie Univ, UNIROUEN, 76000, Rouen, France.
Bouchra LamiaUR3830 GRHVN, Institute for Research and Innovation in Biomedicine (IRIB), Normandie Univ, UNIROUEN, 76000, Rouen, France.
Marius LebretKernel Biomedical, 18 Rue Marie Curie Bâtiment ANIDER, 76000, Rouen, France.
Clément MedrinalIntensive Care Unit Department, Le Havre Hospital, Avenue Pierre Mendes France, 76290, Montivilliers, France. medrinal.clement.mk@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTracheostomized patients often present with muscle weakness, altered consciousness, or swallowing difficulties. Hence, the literature is scarce regarding the challenging management of tracheostomy weaning. There is a need to strengthen the understanding of respiratory mechanisms with the different tracheostomy tube modalities that compose this weaning pathway. We aimed to evaluate the impact of these modalities on the work of breathing (WOB), total positive end-expiratory pressure (PEEPtot), and tidal volume (V

methodsWith a three-dimensional (3D) printed head mimicking human upper airways, we added a tracheal extension, and pierced to allow insertion of a size 7.0 tracheostomy cannula. The whole was connected to an artificial lung. Three lung mechanics were simulated (normal, obstructive and restrictive). We compared five different tracheostomy tube modalities to a control scenario in which the tube was capped and the cuff was deflated.

resultsA marginal difference was observed on the WOB within conditions with a slight increase + 0.004 [95% CI (0.003-0.004); p < 0.001] when the cuff was inflated in the normal and restrictive models and a slight decrease in the obstructive model. The highest PEEPtot that was reached was + 1 cmH

conclusionsOur results support the use of conditions that involve cuff deflation. Intermediate modalities with the cuff deflated produced similar results than cannula capping.

Indexed as

CuffHigh flowSpeaking valveTracheostomyWeaningWork of breathing

Identifiers

PMID38976100
PMCPMC11231115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.