Evidence map›Paper›PMID 38976096›Full record

ArticleIntensive care medicine experimental2024

Mitochondrial oxygen tension in critically ill patients receiving red blood cell transfusions: a multicenter observational cohort study.

M Baysan, B Hilderink, L van Manen, C Caram-Deelder, E G Mik, N P Juffermans, J G van der Bom, M S Arbous

Abstract read
In one paragraph

Article in Intensive care medicine experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M BaysanDepartment of Intensive Care Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-8642-4802
B HilderinkDepartment of Intensive Care Medicine, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-7684-6529
L van ManenDepartment of Intensive Care Medicine, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-6777-7875
C Caram-DeelderDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0003-3161-5684
E G MikDepartment of Anesthesiology, Laboratory of Experimental Anesthesiology, Erasmus MC- University Medical Center Rotterdam, Rotterdam, The Netherlands.
N P JuffermansDepartment of Intensive Care Medicine, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-3039-6574
J G van der BomDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-9095-2475
M S ArbousDepartment of Intensive Care Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. M.S.Arbous@lumc.nl.ORCID http://orcid.org/0000-0001-5242-3257

Funding

Stichting Sanquin Bloedvoorziening PPOC-16-31
6 · The paper itself

Abstract

purposeCurrently, there is no marker of efficacy of red blood cell (RBC) transfusion. This study describes the impact of RBC transfusion on mitochondrial oxygen tension (mitoPO

methodsCritically ill patients with a hemoglobin concentration < 10 g/dL, for whom a single RBC unit had been ordered, were included. MitoPO

resultsSixty-three patients participated, median age 64.0 (interquartile range (IQR) 52.3-72.8) years, median hemoglobin concentration before transfusion 7.4 (IQR 7.1-7.7) g/dL. Median mitoPO

conclusionRBC transfusion did not alter mitoPO

Indexed as

AnemiaMitochondrial oxygen tensionRed blood cell transfusionTissue oxygenation

Identifiers

PMID38976096
PMCPMC11231106

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.