Evidence map›Paper›PMID 38976036›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2024

[

Anqi Li, Ruiyue Zhao, Mingkai Zhang, Pan Sun, Yue Cai, Lin Zhu, Hank Kung, Ying Han, Xinlu Wang, Tengfei Guo

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Association of plasma p-tau and p-tau/Aβ ratio with Alzheimer's pathology.The journal of prevention of Alzheimer's disease · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Recent developments in translational imaging of in vivo gene therapy outcomes.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  12. Plasma N-terminal tau fragment is an amyloid-dependent biomarker in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  13. Diagnostic accuracy of plasma p-tau217/Aβ42 for Alzheimer's disease in clinical and community cohorts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anqi LiInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, No.5 Kelian Road, Shenzhen, 518132, China.
Ruiyue ZhaoDepartment of Nuclear Medicine, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510120, China.
Mingkai ZhangDepartment of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, 100053, China.
Pan SunInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, No.5 Kelian Road, Shenzhen, 518132, China.
Yue CaiInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, No.5 Kelian Road, Shenzhen, 518132, China.
Lin ZhuBeijing Normal University, Beijing, 100875, China.
Hank KungUniversity of Pennsylvania, Philadelphia, PA, 19104, USA.
Ying HanInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, No.5 Kelian Road, Shenzhen, 518132, China.
Xinlu WangDepartment of Nuclear Medicine, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510120, China. 71lu@163.com.
Tengfei GuoInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, No.5 Kelian Road, Shenzhen, 518132, China. tengfei.guo@szbl.ac.cn.ORCID 0000-0003-2982-0865

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2023B1515020113Lingang Laboratory LG-GG-202401-ADA070600National Natural Science Foundation of China 82171197Shenzhen Science and Technology Innovation Program RCYX20221008092935096
6 · The paper itself

Abstract

purpose[

methodsWe recruited 203 participants from the Greater Bay Area Healthy Aging Brain Study (GHABS) to undergo [

resultsBrainstem/PONs SUV showed the lowest fluctuation across diagnostic groups, and COMPOSITE D3FSP SUVR had an enormous effect distinguishing cognitively impaired (CI) individuals from cognitively unimpaired (CU) individuals. COMPOSITE SUVR (Referred to brainstem/PONs) was positively correlated with p-Tau

conclusionThis study suggests brainstem/PONs as an optimal reference region for calculating D3FSP SUVR to quantify cortical Aβ plaques in the brain. [

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesPositron-Emission TomographyAgedAged, 80 and overBiomarkersBrainFemaleHumansMaleMiddle AgedAmyloid beta-PeptidesBiomarkersAlzheimer’s diseaseD3FSP Aβ PETPlasma biomarkersReference regionTau PET

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.