Evidence map›Paper›PMID 38975761›Full record

ArticlemSphere2024

Gene-specific transcriptional activation by the

Shivani Ror, Mark A Stamnes, W Scott Moye-Rowley

Abstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shivani RorDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Mark A StamnesDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
W Scott Moye-RowleyDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-7163-1120

Funding

Elevated gene transcription of the cyp51A gene is essential for azole drug resistance in Aspergillus fumigatusR01AI143198 · NIAID · UNIVERSITY OF IOWA · PI W Scott Moye-Rowley · 2019 to 2026
$3.9M
Transcriptional networks governing A. fumigatus virulenceR01AI162802 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MOYE-ROWLEY, W SCOTT · 2021 to 2025
$3.3M
NIAID NIH HHS R01 AI143198NIAID NIH HHS R01 AI162802
6 · The paper itself

Abstract

Treatment of fungal infections associated with the filamentous fungus IMPORTANCE:

Indexed as

Antifungal AgentsAspergillus fumigatusFungal ProteinsGene Expression Regulation, FungalTranscriptional ActivationAzolesCytochrome P-450 Enzyme SystemDrug Resistance, FungalProtein DomainsTranscription FactorsAntifungal AgentsAzolescytochrome P-450 CYP51A, AspergillusCytochrome P-450 Enzyme SystemFungal ProteinsTranscription FactorsAspergillus fumigatusazole resistancegene expressiontranscriptional regulation

Identifiers

PMID38975761
PMCPMC11288021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.