Evidence map›Paper›PMID 38975623›Full record

ArticleClinical cardiology2024

Comparison of Outcomes of Edge-to-Edge Mitral Valve Repair Versus Surgical Mitral Valve Repair for Functional Mitral Regurgitation.

Xiqiang Wang, Yanpeng Ma, Zhongwei Liu, Ling Zhu, Junkui Wang, Gongchang Guan, Shuo Pan, Yong Zhang, Yuanyuan Hao

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Clinical cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Xiqiang WangKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, Xi'an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University, Xi'an, Shaanxi, People's Republic of China.
Yanpeng MaDepartment of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.
Zhongwei LiuDepartment of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.
Ling ZhuDepartment of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.
Junkui WangDepartment of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.
Gongchang GuanDepartment of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.
Shuo PanDepartment of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.ORCID http://orcid.org/0000-0001-7934-572X
Yong ZhangDepartment of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.
Yuanyuan HaoDepartment of Cardiovascular Medicine, Xi'an Central Hospital, Xi'an, Shaanxi, People's Republic of China.

Funding

Xiqiang Wang was supported by the Technology Talents Support Program of Shaanxi Provincial People's Hospital (2023JY-13), the China Postdoctoral Science Foundation (2022M722576), Shaanxi Provincial Postdoctoral Foundation first-class support (No.127), and the Xi'an Innovation Ability Support Plan (23YXYJ0187). Yanpeng Ma was supported by the Technology Talents Support Program of Shaanxi Provincial People's Hospital (2022JY-52). Shuo Pan was funded by the Top Talent Program of Shaanxi Provincial People's Hospital (2021BJ-12) and the Innovative Talents Promotion Program-Young Science and Technology Nova Project of Shaanxi province (2020KJXX-086). Yuanyuan Hao was funded by the Xi'an Postdoctoral Innovation base project (20180823) and Basic Scientific Research Operating Expenses of Xi'an Jiaotong University (xzy012021080).
6 · The paper itself

Abstract

aimsPatients affected by functional mitral regurgitation represent an increasingly high-risk population. Edge-to-edge mitral valve repair (TEER) has emerged as a promising treatment option for these patients. However, there is limited research on the comparative outcomes of TEER versus surgical mitral valve repair (SMVr). This study seeks to compare the demographics, complications, and outcomes of TEER and SMVr based on a real-world analysis of the National Inpatient Sample (NIS) database. METHODS AND

resultsIn the NIS database, from the years 2016 to 2018, a total of 6233 and 2524 patients who underwent SMVr and TEER were selected, respectively. The mean ages of the patients were 65.68 years (SMVr) and 78.40 years (TEER) (p < 0.01). The mortality rate of patients who received SMVr was similar to that of patients who were treated with TEER (1.7% vs. 1.9%, p = 0.603). Patients who underwent SMVr more likely suffered from perioperative complications including cardiogenic shock (2.3% vs. 0.4%, p < 0.001), cardiac arrest (1.7% vs. 1.1%, p = 0.025), and cerebrovascular infarction (0.9% vs. 0.4%, p = 0.013). The average length of hospital stay was longer (8.59 vs. 4.13 days, p < 0.001) for SMVr compared to TEER; however, the average cost of treatment was higher ($218 728.25 vs. $215 071.74, p = 0.031) for TEER compared to SMVr. Multiple logistic regression analysis showed that SMVr was associated with worse adjusted cardiogenic shock (OR, 7.347 [95% CI, 3.574-15.105]; p < 0.01) and acute kidney injury (OR, 2.793 [95% CI, 2.356-3.311]; p < 0.01).

conclusionPatients who underwent TEER demonstrated a notable decrease in postoperative complications and a shorter hospitalization period when compared to those who underwent SMVr.

Indexed as

Heart Valve Prosthesis ImplantationMitral ValveMitral Valve InsufficiencyPostoperative ComplicationsAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedMitral Valve AnnuloplastyRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited Statesedge‐to‐edge mitral valve repairmitral insufficiencysurgical mitral valve repair

Identifiers

PMID38975623
PMCPMC11228827

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.