Evidence map›Paper›PMID 38975457›Full record

ArticleCureus2024

Going Outside the Gut: Immune Thrombocytopenia Presenting as a Rare Extraintestinal Manifestation of Ulcerative Colitis.

Ana P Rivera, James R Pellegrini, Tulika Saggar, Melvin V Joy, Atul Sinha, Sandra Gomez, Kaleem Rizvon

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana P RiveraInternal Medicine, Nassau University Medical Center, East Meadow, USA.
James R PellegriniGastroenterology and Hepatology, Nassau University Medical Center, East Meadow, USA.
Tulika SaggarInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Melvin V JoyInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Atul SinhaGastroenterology and Hepatology, Nassau University Medical Center, East Meadow, USA.
Sandra GomezGastroenterology and Hepatology, Nassau University Medical Center, East Meadow, USA.
Kaleem RizvonGastroenterology and Hepatology, Nassau University Medical Center, East Meadow, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 26-year-old male with no significant medical history presented with hematochezia and was diagnosed with ulcerative colitis (UC) accompanied by immune thrombocytopenia (ITP) as an extraintestinal manifestation (EIM) of UC. This case report delves into the uncommon overlap between UC, a subtype of inflammatory bowel disease primarily affecting the colon and rectum, and ITP, an autoimmune condition leading to platelet destruction. The patient's atypical presentation and subsequent positive response to a treatment regimen targeting both UC and ITP underscores the necessity for a thorough and multifaceted diagnostic approach in individuals with UC, especially when faced with non-gastrointestinal symptoms like unexplained thrombocytopenia. The findings from this study enhance the understanding of UC's diverse manifestations and highlight its potential intersection with other autoimmune diseases, advocating for integrated care strategies in managing such intricate clinical cases.

Indexed as

autoimmune colitisextraintestinal manifestationsextraintestinal manifestations in inflammatory bowel diseasehematologic autoimmune disorders(ibd) inflammatory bowel diseaseimmune thrombocytopenia (itp)intravenous immunoglobulin (ivig)mesalamine therapythrombocytopeniaulcerative colitis (uc)

Identifiers

PMID38975457
PMCPMC11227741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.