Evidence map›Paper›PMID 38975247›Full record

ArticleOpen forum infectious diseases2024

Recurrent

Nirja Mehta, Dana Goodenough, Nitin K Gupta, Stepy Thomas, Christina Mehta, Radhika Prakash, Michael H Woodworth, Colleen S Kraft, Scott K Fridkin

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Microbiome-based therapeutics for Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nirja MehtaDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-6324-0077
Dana GoodenoughGeorgia Emerging Infections Program, Decatur, Georgia, USA.
Nitin K GuptaAtlanta Gastroenterology Associates, Georgia, USA.
Stepy ThomasGeorgia Emerging Infections Program, Decatur, Georgia, USA.
Christina MehtaDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Radhika PrakashDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Michael H WoodworthDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Colleen S KraftDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Scott K FridkinDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
J: NRSA Training CoreTL1TR002382 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Vasiliki Michopoulos · 2017 to 2026
$8.5M
Temporal dynamics of MDRO eradication after FMTK23AI144036 · NIAID · EMORY UNIVERSITY · PI WOODWORTH, MICHAEL HOLMES · 2019 to 2023
$957k
ACL HHS U54CK000485NCATS NIH HHS TL1 TR002382NCATS NIH HHS UL1 TR002378NCEZID CDC HHS U54 CK000485NCPDCID CDC HHS U01 CI000906NIAID NIH HHS K23 AI144036
6 · The paper itself

Abstract

Background: Fecal microbiota transplantation (FMT) is recommended for the treatment of recurrent Methods: A retrospective community-wide cohort study was conducted using surveillance data from the Georgia Emerging Infections Program, the Georgia Discharge Data System, and locally maintained lists of FMTs completed across multiple institutions to evaluate all episodes of Results: A total of 3038 (22%) of 13 852 patients with CDI had rCDI during this period. In a propensity-matched cohort, patients who received an FMT had lower rates of rCDI (odds ratio, 0.6 [95% confidence interval, .38-.96) and a lower mortality rate (0.26 [.08-.82]). Of patients with rCDI, only 6% had received FMT. Recipients were more likely to be young, white, and female and less likely to have renal disease, diabetes, or liver disease, though these chronic illnesses were associated with higher rates of rCDI. Conclusions: These data suggest FMT has been underused in a population-based assessment and that FMT substantially reduced risk of recurrence and death.

Indexed as

clostridioides difficileemerging infections programfecal microbiota transplantationreal-world therapy utilizationrecurrent clostridioides difficile

Identifiers

PMID38975247
PMCPMC11227225

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.