Evidence map›Paper›PMID 38975245›Full record

ReviewFrontiers in neuroscience2024

Research advances in huntingtin-associated protein 1 and its application prospects in diseases.

Yongjiang Wu, Yanfei Wang, Yunchi Lu, Junguo Yan, Hongjun Zhao, Riyun Yang, Jingying Pan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Psychosis in Huntington disease: a short update.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yongjiang Wu *Department of Histology and Embryology, Medical School of Nantong University, Nantong, China.
Yanfei Wang *Department of Histology and Embryology, Medical School of Nantong University, Nantong, China.
Yunchi LuDepartment of Histology and Embryology, Medical School of Nantong University, Nantong, China.
Junguo YanDepartment of Histology and Embryology, Medical School of Nantong University, Nantong, China.
Hongjun ZhaoDepartment of Histology and Embryology, Medical School of Nantong University, Nantong, China.
Riyun YangDepartment of Histology and Embryology, Medical School of Nantong University, Nantong, China.
Jingying PanDepartment of Histology and Embryology, Medical School of Nantong University, Nantong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntingtin-associated protein 1 (HAP1) was the first protein discovered to interact with huntingtin. Besides brain, HAP1 is also expressed in the spinal cord, dorsal root ganglion, endocrine, and digestive systems. HAP1 has diverse functions involving in vesicular transport, receptor recycling, gene transcription, and signal transduction. HAP1 is strongly linked to several neurological diseases, including Huntington's disease, Alzheimer's disease, epilepsy, ischemic stroke, and depression. In addition, HAP1 has been proved to participate in cancers and diabetes mellitus. This article provides an overview of HAP1 regarding the tissue distribution, cell localization, functions, and offers fresh perspectives to investigate its role in diseases.

Indexed as

cancerdiabetes mellitushuntingtin-associated protein 1neurological diseasesneuropathology

Identifiers

PMID38975245
PMCPMC11224548

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.