Evidence map›Paper›PMID 38975024›Full record

ReviewMed-X2024

Engineering biomaterials by inkjet printing of hydrogels with functional particulates.

Cih Cheng, Eric J Williamson, George T-C Chiu, Bumsoo Han

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Med-X, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cih ChengSchool of Mechanical Engineering, Purdue University, West Lafayette, IN USA.
Eric J WilliamsonSchool of Mechanical Engineering, Purdue University, West Lafayette, IN USA.
George T-C ChiuSchool of Mechanical Engineering, Purdue University, West Lafayette, IN USA.
Bumsoo HanSchool of Mechanical Engineering, Purdue University, West Lafayette, IN USA.ORCID 0000-0001-9487-1090

Funding

Reprogramming PDAC Stroma by Targeting Coagulation in the Tumor MicroenvironmentU01CA274304 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Melissa L. Fishel, Matthew J. Flick · 2022 to 2026
$4.6M
Targeting the Plasminogen Activation System to Limit Pancreatic Cancer Progression and Associated ThrombosisU01HL143403 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FISHEL, MELISSA L., FLICK, MATTHEW J. · 2018 to 2022
$4.2M
Investigation of novel signaling protein in 3D and in vivo PDAC models using second generation Ref-1 inhibitorsR01CA254110 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI FISHEL, MELISSA L., HAN, BUMSOO · 2021 to 2025
$2.1M
Dynamic Circadian Regulation of the Blood-Brain Interface in a Human Brain-mimicking Microfluid ChipR33HL159948 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GILLETTE, MARTHA U, HAN, BUMSOO · 2023 to 2025
$1.4M
NCI NIH HHS R01 CA254110NCI NIH HHS U01 CA274304NHLBI NIH HHS R33 HL159948NHLBI NIH HHS U01 HL143403
6 · The paper itself

Abstract

Hydrogels with particulates, including proteins, drugs, nanoparticles, and cells, enable the development of new and innovative biomaterials. Precise control of the spatial distribution of these particulates is crucial to produce advanced biomaterials. Thus, there is a high demand for manufacturing methods for particle-laden hydrogels. In this context, 3D printing of hydrogels is emerging as a promising method to create numerous innovative biomaterials. Among the 3D printing methods, inkjet printing, so-called drop-on-demand (DOD) printing, stands out for its ability to construct biomaterials with superior spatial resolutions. However, its printing processes are still designed by trial and error due to a limited understanding of the ink behavior during the printing processes. This review discusses the current understanding of transport processes and hydrogel behaviors during inkjet printing for particulate-laden hydrogels. Specifically, we review the transport processes of water and particulates within hydrogel during ink formulation, jetting, and curing. Additionally, we examine current inkjet printing applications in fabricating engineered tissues, drug delivery devices, and advanced bioelectronics components. Finally, the challenges and opportunities for next-generation inkjet printing are also discussed. Graphical Abstract:

Indexed as

BioelectronicsDrop-on-demand printingDrug delivery deviceParticle transportTissue engineeringWater-matrix interaction

Identifiers

PMID38975024
PMCPMC11222244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.