Evidence map›Paper›PMID 38974930›Full record

ArticleResuscitation plus2024

A protocol for the ERICA-ARREST feasibility study of Emergency Resuscitative Endovascular Balloon occlusion of the Aorta in Out-of-Hospital Cardiac Arrest.

Shadman Aziz, Jon Barratt, Noamaan Wilson-Baig, Kate Lachowycz, Rob Major, Ed B G Barnard, Paul Rees

Registry-linked trialAbstract read
In one paragraph

Article in Resuscitation plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06071910 (Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06071910 narecruitingnot on this map

Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest

TypeinterventionalSponsorQueen Mary University of LondonRan2024 to 2026Enrolled40ConditionsOut-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrhythmia, Ventricular FibrillationArmsER-REBOA catheter
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Endovascular resuscitation: an expert practice review.Emergency medicine journal : EMJ · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. A scoping review of cognitive load assessment tools suitable for clinicians performing REBOA.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shadman AzizDepartment of Research, Audit, Innovation, and Development (RAID). East Anglian Air Ambulance, Norwich, UK.
Jon BarrattDepartment of Research, Audit, Innovation, and Development (RAID). East Anglian Air Ambulance, Norwich, UK.
Noamaan Wilson-BaigDepartment of Research, Audit, Innovation, and Development (RAID). East Anglian Air Ambulance, Norwich, UK.
Kate LachowyczDepartment of Research, Audit, Innovation, and Development (RAID). East Anglian Air Ambulance, Norwich, UK.
Rob MajorDepartment of Research, Audit, Innovation, and Development (RAID). East Anglian Air Ambulance, Norwich, UK.
Ed B G BarnardDepartment of Research, Audit, Innovation, and Development (RAID). East Anglian Air Ambulance, Norwich, UK.
Paul ReesDepartment of Research, Audit, Innovation, and Development (RAID). East Anglian Air Ambulance, Norwich, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fewer than one in ten out-of-hospital cardiac arrest (OHCA) patients survive to hospital discharge in the UK. For prehospital teams to improve outcomes in patients who remain in refractory OHCA despite advanced life support (ALS); novel strategies that increase the likelihood of return of spontaneous circulation, whilst preserving cerebral circulation, should be investigated. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) has been shown to improve coronary and cerebral perfusion during cardiopulmonary resuscitation. Early, prehospital initiation of REBOA may improve outcomes in patients who do not respond to standard ALS. However, there are significant clinical, technical, and logistical challenges with rapidly delivering prehospital REBOA in OHCA; and the feasibility of delivering this intervention in the UK urban-rural setting has not been evaluated. Methods: The Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out-of-Hospital Cardiac Arrest (ERICA-ARREST) study is a prospective, single-arm, interventional feasibility study. The trial will enrol 20 adult patients with non-traumatic OHCA. The primary objective is to assess the feasibility of performing Zone I (supra-coeliac) aortic occlusion in patients who remain in OHCA despite standard ALS in the UK prehospital setting. The trial's secondary objectives are to describe the hemodynamic and physiological responses to aortic occlusion; to report key time intervals; and to document adverse events when performing REBOA in this context. Discussion: Using compressed geography, and targeted dispatch, alongside a well-established femoral arterial access programme, the ERICA-ARREST study will assess the feasibility of deploying REBOA in OHCA in a mixed UK urban and rural setting.Trial registration.ClinicalTrials.gov (NCT06071910), registration date October 10, 2023, https://classic.clinicaltrials.gov/ct2/show/NCT06071910.

Indexed as

FeasibilityHEMSOut-of-hospital cardiac arrestPrehospitalProtocolREBOA

Identifiers

PMID38974930
PMCPMC11225899

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.