Evidence map›Paper›PMID 38974872›Full record

ArticleaBIOTECH2024

Developing a CRISPR/FrCas9 system for core promoter editing in rice.

Hui Wang, Jian Ding, Jingyan Zhu, Xiaoshuang Liu, Rongfang Xu, Ruiying Qin, Dongfang Gu, Min Li, Pengcheng Wei, Juan Li

Abstract read
In one paragraph

Article in aBIOTECH, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Genome Editing Approaches in Flax (International journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. CRISPR-Cas applications in agriculture and plant research.Nature reviews. Molecular cell biology · 2025
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hui Wang *College of Agronomy, Anhui Agricultural University, Hefei, 230036 China.
Jian Ding *College of Agronomy, Anhui Agricultural University, Hefei, 230036 China.
Jingyan Zhu *College of Agronomy, Anhui Agricultural University, Hefei, 230036 China.
Xiaoshuang LiuCollege of Agronomy, Anhui Agricultural University, Hefei, 230036 China.
Rongfang XuKey Laboratory of Rice Genetic Breeding of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230031 China.
Ruiying QinKey Laboratory of Rice Genetic Breeding of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230031 China.
Dongfang GuKey Laboratory of Rice Genetic Breeding of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230031 China.
Min LiCollege of Agronomy, Anhui Agricultural University, Hefei, 230036 China.
Pengcheng WeiCollege of Agronomy, Anhui Agricultural University, Hefei, 230036 China.ORCID 0000-0001-5403-9451
Juan LiKey Laboratory of Rice Genetic Breeding of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230031 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small mutations in the core promoter region of a gene may result in substantial changes in expression strengths. However, targeting TA-rich sequences of core promoters may pose a challenge for Cas9 variants such as SpCas9 and other G-rich PAM-compatible Cas9s. In this study, we engineered a unique FrCas9 system derived from Supplementary Information: The online version contains supplementary material available at 10.1007/s42994-024-00157-5.

Indexed as

Base editingCore promoterCRISPRFrCas9Genome editing

Identifiers

PMID38974872
PMCPMC11224051

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.