Evidence map›Paper›PMID 38974807›Full record

ArticleRevista panamericana de salud publica = Pan American journal of public health2024

National and regional population attributable fractions for anemia risk factors (iron, folate, and vitamin B12) in Belize: potential impact of fortification.

Jorge Rosenthal, Clinton J Alverson, Natalia Largaespada-Beer, Gail Pa Kauwell, Lynn B Bailey, Julio J Sabido, Melissa Diaz, Jennifer L Williams, Kevin Bernard

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Article in Revista panamericana de salud publica = Pan American journal of public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Jorge RosenthalU.S. Centers for Disease Control and Prevention Atlanta, GA United States of America U.S. Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Clinton J AlversonU.S. Centers for Disease Control and Prevention Atlanta, GA United States of America U.S. Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Natalia Largaespada-BeerMinistry of Health and Wellness Belmopan Belize Ministry of Health and Wellness, Belmopan, Belize.
Gail Pa KauwellUniversity of Central Florida Orlando, FL United States of America University of Central Florida, Orlando, FL, United States of America.
Lynn B BaileyUniversity of Georgia Athens, GA United States of America University of Georgia, Athens, GA, United States of America.
Julio J SabidoMinistry of Health and Wellness Belmopan Belize Ministry of Health and Wellness, Belmopan, Belize.
Melissa DiazMinistry of Health and Wellness Belmopan Belize Ministry of Health and Wellness, Belmopan, Belize.
Jennifer L WilliamsU.S. Centers for Disease Control and Prevention Atlanta, GA United States of America U.S. Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Kevin BernardMinistry of Health and Wellness Belmopan Belize Ministry of Health and Wellness, Belmopan, Belize.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To estimate the national and regional population attributable fraction (PAF) and potential number of preventable anemia cases for three nutritional risk factors (iron, red blood cell folate [RBCF], and vitamin B12 deficiencies) among women of childbearing age in Belize. Methods: A national probability-based household and micronutrient survey capturing sociodemographic and health information was conducted among 937 nonpregnant Belizean women aged 15-49 years. Blood samples were collected to determine hemoglobin, ferritin, alpha-1-glycoprotein (AGP), RBCF, and vitamin B12 status. All analyses used sample weights and design variables to reflect a complex sample survey. Logistic regression was used to determine adjusted prevalence risk (aPR) ratios, which were then used to estimate national and regional PAF for anemia. Results: The overall prevalence of anemia (hemoglobin <12 g/dL) was 21.2% (95% CI [18.7, 25.3]). The prevalence of anemia was significantly greater among women with iron deficiency (59.5%, 95% CI [48.7, 69.5]) compared to women without iron deficiency (15.2%, 95% CI [12.2, 18.3]; aPR 3.9, 95% CI [2.9, 5.1]). The three nutritional deficiencies examined contributed to 34.6% (95% CI [22.1, 47.1]) of the anemia cases. If all these nutritional deficiencies could be eliminated, then an estimated 5 953 (95% CI [3 807, 8 114]) anemia cases could be prevented. Conclusions: This study suggests that among women of child-bearing age in Belize, anemia cases might be reduced by a third if three modifiable nutritional risk factors (iron, RBCF, and vitamin B12 deficiencies) could be eliminated. Fortification is one potential strategy to improve nutritional status and reduce the burden of anemia in this population.

Indexed as

Anemiaanemia, iron deficiencyBelizefolic acidrisk factorsvitamin B 12 deficiencywomen’s health

Identifiers

PMID38974807
PMCPMC11225218

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