Evidence map›Paper›PMID 38974772›Full record

ArticleJournal of molecular and cellular cardiology plus2024

Dietary linoleic acid supplementation fails to rescue established cardiomyopathy in Barth syndrome.

Siting Zhu, Jing Pang, Anh Nguyen, Helen Huynh, Sharon Lee, Yusu Gu, Frederic M Vaz, Xi Fang

Abstract read
In one paragraph

Article in Journal of molecular and cellular cardiology plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Cross-species evidence for cardiolipin remodeling in neonatal hypoxic-ischemic encephalopathy.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siting ZhuDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Jing PangDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Anh NguyenDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Helen HuynhDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Sharon LeeDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Yusu GuDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Frederic M VazLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Departments of Clinical Chemistry and Pediatrics, Amsterdam Gastroenterology Endocrinology Metabolism, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.
Xi FangDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.

Funding

NEDD4 in right ventricular developmentR01HL158761 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FANG, XI · 2021 to 2025
$2.5M
Molecular mechanisms and treatment of cardiomyopathy in Barth SyndromeR01HL157115 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FANG, XI · 2021 to 2025
$2.0M
The role of GATAD1 in cardiomyocyte and cardiomyopathyR03TR004997 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FANG, XI · 2024 to 2024
$158k
NCATS NIH HHS R03 TR004997NHLBI NIH HHS R01 HL157115NHLBI NIH HHS R01 HL158761
6 · The paper itself

Abstract

Barth syndrome (BTHS) is a mitochondrial lipid disorder caused by mutations in

Indexed as

Barth syndromeCardiomyopathiesDietary supplementsLinoleic acid

Identifiers

PMID38974772
PMCPMC11225933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.