Evidence map›Paper›PMID 38974740›Full record

ArticleJournal of obstetrics and gynaecology of India2024

Radical Oophorectomy for Advanced Ovarian Cancer: A Feasibility Study from Tertiary Care Cancer Centre in Eastern India.

Sony Nanda, Manoranjan Mahapatra, Janmejaya Mohapatra, Ashok Padhy, Bhagyalaxmi Nayak, Jita Parija

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Article in Journal of obstetrics and gynaecology of India, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Sony NandaDepartment of Gynaecologic Oncology, Acharya Harihara Institute Of Cancer, Cuttack, Odisha India.
Manoranjan MahapatraDepartment of Gynaecologic Oncology, Acharya Harihara Institute Of Cancer, Cuttack, Odisha India.
Janmejaya MohapatraDepartment of Gynaecologic Oncology, Acharya Harihara Institute Of Cancer, Cuttack, Odisha India.
Ashok PadhyDepartment of Gynaecologic Oncology, Acharya Harihara Institute Of Cancer, Cuttack, Odisha India.
Bhagyalaxmi NayakDepartment of Gynaecologic Oncology, Acharya Harihara Institute Of Cancer, Cuttack, Odisha India.
Jita ParijaDepartment of Gynaecologic Oncology, Acharya Harihara Institute Of Cancer, Cuttack, Odisha India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Radical oophorectomy was first performed by Hudson in order to remove an "intact ovarian tumour lodged in the pelvis, with the entire peritoneum remaining attached". We report 16 cases of radical oophorectomy done at our institute in the past 3 years and have analysed the perioperative morbidity as well as feasibility of performing the surgery without much of perioperative complication. Methods: Twenty-three patients with advanced ovarian cancer who underwent modified en bloc pelvic resection at our institute, between November 2018 and October 2021, were initially enrolled. Patients below 70 years, resectable disease on CT scan and no significant comorbidities were included. Exclusion criteria were extra-abdominal metastasis, secondary cancers or complete intestinal obstruction. Initially, 23 patients were enrolled out of which seven patients were excluded. Hence, a total of 16 patients with ovarian cancer extensively infiltrating into nearby pelvic organs and peritoneum were included. In Type 1 radical oophorectomy, retrograde modified radical hysterectomy alongwith in toto removal of the bilateral adnexae, pelvic cul-de-sac and affected pelvic peritoneum is done. Type 2 radical oophorectomy includes total parietal and visceral pelvic peritonectomy as well as an en bloc resection of the rectosigmoid colon below the peritoneal reflection. Results: Radical oophorectomy is feasible with acceptable complication rate. In our study, only one patient had burst abdomen that too due to the poor nutritional status of the patient. There was no surgery-related deaths, but one patient succumbed to pulmonary embolism 5 days after the operation. Conclusion: Hence, radical oophorectomy proves to be an effective, feasible and secure surgical technique in cases of advanced ovarian malignancies with extensive involvement of peritoneum, pelvis and visceras.

Indexed as

En bloc pelvic resectionEpithelial ovarian cancerHudson methodRadical oophorectomy

Identifiers

PMID38974740
PMCPMC11224057

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