Evidence map›Paper›PMID 38974505›Full record

ArticleJournal of respiratory biology and translational medicine2024

A Novel Animal Model for Pulmonary Hypertension: Lung Endothelial-Specific Deletion of

Bin Liu, Dan Yi, Xiaokuang Ma, Karina Ramirez, Hanqiu Zhao, Xiaomei Xia, Michael B Fallon, Vladimir V Kalinichenko, Shenfeng Qiu, Zhiyu Dai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of respiratory biology and translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Intracellular Chloride Channels: A Rising Target in Lung Disease Research.Journal of respiratory biology and translational medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bin LiuDivision of Pulmonary, Critical Care and Sleep, University of Arizona, Phoenix, AZ 85004, USA.
Dan YiDivision of Pulmonary, Critical Care and Sleep, University of Arizona, Phoenix, AZ 85004, USA.
Xiaokuang MaBasic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85004, USA.
Karina RamirezDivision of Pulmonary, Critical Care and Sleep, University of Arizona, Phoenix, AZ 85004, USA.
Hanqiu ZhaoDivision of Pulmonary, Critical Care and Sleep, University of Arizona, Phoenix, AZ 85004, USA.
Xiaomei XiaDivision of Pulmonary, Critical Care and Sleep, University of Arizona, Phoenix, AZ 85004, USA.
Michael B FallonDepartment of Internal Medicine, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85004, USA.
Vladimir V KalinichenkoDivision of Neonatology, Phoenix Children's Hospital, Phoenix, AZ 85016, USA.
Shenfeng QiuBasic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85004, USA.
Zhiyu DaiDivision of Pulmonary, Critical Care and Sleep, University of Arizona, Phoenix, AZ 85004, USA.

Funding

Transcriptional Regulation of Endothelial Cells after Neonatal Lung InjuryR01HL141174 · NHLBI · UNIVERSITY OF ARIZONA · PI Vladimir Kalinichenko · 2018 to 2026
$4.7M
Novel alveolar mechanisms of hypoxemia in hepatopulmonary syndromeR01HL169509 · NHLBI · UNIVERSITY OF ARIZONA · PI Zhiyu Dai, MICHAEL B FALLON · 2023 to 2026
$3.0M
General Capillary to Arterial Endothelial Cell Transition in Pulmonary ArterialHypertensionR01HL170096 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2023 to 2026
$2.9M
Role of Endothelial SOX17 Deficiency in the Pathogenesis of Pulmonary HypertensionR01HL158596 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2022 to 2026
$2.3M
Fatty acid-binding proteins sustain endothelial glycolysis and arterial programming in pulmonary arterial hypertensionR01HL162794 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2023 to 2026
$2.3M
Role of Smooth Muscle Progenitor Cells in Obliterative Vascular Remodeling and PHR00HL138278 · NHLBI · UNIVERSITY OF ARIZONA · PI DAI, ZHIYU · 2019 to 2021
$747k
NHLBI NIH HHS R00 HL138278NHLBI NIH HHS R01 HL141174NHLBI NIH HHS R01 HL158596NHLBI NIH HHS R01 HL162794NHLBI NIH HHS R01 HL169509NHLBI NIH HHS R01 HL170096
6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) is a devastating disease characterized by high blood pressure in the pulmonary arteries, which can potentially lead to heart failure over time. Previously, our lab found that endothelia-specific knockout of

Indexed as

Endothelial cellsHypoxiaPulmonary arterial hypertensionRight heartTMEM100

Identifiers

PMID38974505
PMCPMC11225937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.