Evidence map›Paper›PMID 38974182›Full record

ArticleClinical case reports2024

Spontaneous coronary artery dissection in the context of tamoxifen; Is there any correlation?

Homina Saffar, Leili Abdan, Zahra Abdan, Hamidreza Hekmat, Alireza Amirzadegan, Negar Omidi

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Vascular Toxicities of Cancer Therapies: 2025 Update.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Homina SaffarStudent Research Committee, Faculty of Medicine Mazandaran University of Medical Sciences Sari Iran.ORCID https://orcid.org/0000-0002-2193-0608
Leili AbdanCardiovascular Disease Research Institute, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0003-3209-5262
Zahra AbdanClinical Research Development Center Imam Reza Hospital, Kermanshah University of Medical Sciences Kermanshah Iran.ORCID https://orcid.org/0000-0003-1773-5495
Hamidreza HekmatSchool of Medicine, baharloo Hospital, International Campus, Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-3834-9203
Alireza AmirzadeganTehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Science Tehran Iran.ORCID https://orcid.org/0000-0003-1751-019X
Negar OmidiCardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Science Tehran Iran.ORCID https://orcid.org/0000-0003-2344-1661

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key Clinical Message: Clinicians should consider spontaneous coronary artery dissection in middle-aged women presenting with acute coronary syndromes and a history of tamoxifen use, to ensure timely diagnosis, and appropriate management strategies. Abstract: Spontaneous coronary artery dissection (SCAD) is characterized by a non-iatrogenic, nontraumatic separation of the coronary artery wall, contributing to acute coronary syndromes (ACS), and sudden cardiac death. SCAD predominantly affects the left anterior descending artery (LAD) and is frequently observed in middle-aged women. This condition has been associated with cancer treatment and exogenous hormones exposure. The diagnostic gold standard remains coronary angiography, management strategies include conservative measures, percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABG). We describe a case of a 54-year-old woman with breast cancer and a history of tamoxifen use, presenting with SCAD in the posterolateral branch (PLB) originating from the left circumflex artery (LCX), and right coronary artery (RCA) and managed conservatively.

Indexed as

acute coronary syndromebreast cancerchest painmyocardial infarctionspontaneous coronary artery dissectiontamoxifen

Identifiers

PMID38974182
PMCPMC11224767

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.