Evidence map›Paper›PMID 38973993›Full record

ArticleBioactive materials2024

Fabricating oxygen self-supplying 3D printed bioactive hydrogel scaffold for augmented vascularized bone regeneration.

Yang Yang, Wanmeng Wang, Qianrui Zeng, Ning Wang, Wenbo Li, Bo Chen, Qingxin Guan, Changyi Li, Wei Li

Abstract read
In one paragraph

Article in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Artificial intelligence virtual bone organoids (AIVBOs).Journal of orthopaedic translation · 2026
    Review
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  7. Review
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  14. Review
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  16. Review
  17. Bone organoid construction and evolution.Journal of orthopaedic translation · 2025
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yang YangState Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), College of Chemistry, Nankai University, Tianjin, 300071, PR China.
Wanmeng WangTianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, School of Stomatology, Tianjin Medical University, Tianjin, 300071, PR China.
Qianrui ZengState Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), College of Chemistry, Nankai University, Tianjin, 300071, PR China.
Ning WangTianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, School of Stomatology, Tianjin Medical University, Tianjin, 300071, PR China.
Wenbo LiState Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), College of Chemistry, Nankai University, Tianjin, 300071, PR China.
Bo ChenTianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, School of Stomatology, Tianjin Medical University, Tianjin, 300071, PR China.
Qingxin GuanState Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), College of Chemistry, Nankai University, Tianjin, 300071, PR China.
Changyi LiTianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, School of Stomatology, Tianjin Medical University, Tianjin, 300071, PR China.
Wei LiState Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), College of Chemistry, Nankai University, Tianjin, 300071, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited cells and factors, inadequate mechanical properties, and necrosis of defects center have hindered the wide clinical application of bone-tissue engineering scaffolds. Herein, we construct a self-oxygenated 3D printed bioactive hydrogel scaffold by integrating oxygen-generating nanoparticles and hybrid double network hydrogel structure. The hydrogel scaffold possesses the characteristics of extracellular matrix; Meanwhile, the fabricated hybrid double network structure by polyacrylamide and CaCl

Indexed as

3D printingBioactive hydrogelBone tissue engineeringLong-term oxygen-generatingVascularized bone regeneration

Identifiers

PMID38973993
PMCPMC11226730

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.