ArticleAmerican journal of epidemiology2025
The health implications of cumulative exposure to contextual (dis)advantage: methodological and substantive advances from a unique data linkage.
Article in American journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- How does life course exposure to contextual disadvantage accelerate biological aging? The role of psychological symptoms.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Cumulative neighborhood disadvantage and racial and geographic disparities in epigenetic aging.SSM - population health · 2025Article
- Xu et al respond to "Invited commentary: improving spatial exposure data for everyone-life-course social context and ascertaining residential history".American journal of epidemiology · 2025Article
- Linking sequences of exposure to residential (dis)advantage, individual socioeconomic status, and health.Health & place · 2024Article
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Authors and funding
7 authors.
Funding
Abstract
Deleterious neighborhood conditions are associated with poor health, yet the health impact of cumulative lifetime exposure to neighborhood disadvantage is understudied. Using up to 5 decades of residential histories for 4177 adult participants in the Survey of the Health of Wisconsin (SHOW) and spatiotemporally linked neighborhood conditions, we developed 4 operational approaches to characterizing cumulative neighborhood (dis)advantage over the life course. We estimated their associations with self-reported general health and compared them with estimates using neighborhood (dis)advantage at the time of study enrollment. When cumulative exposures were assessed with the most granular temporal scale (approach 4), neighborhood transportation constraints (odds ratio [OR] = 1.21; 95% CI, 1.08-1.36), residential turnover (OR = 1.20; 95% CI, 1.07-1.34), education deficit (OR = 1.17; 95% CI, 1.04-1.32), racial segregation (OR = 1.20; 95% CI, 1.04-1.38), and median household income (OR = 0.85; 95% CI, 0.75-0.97) were significantly associated with risk of fair or poor health. For composite neighborhood disadvantage, cumulative exposures had a stronger association (OR = 1.05; 95% CI, 1.02-1.08) than the cross-sectional exposure (OR = 1.03; 95% CI, 1.01-1.06). Single-point-in-time neighborhood measures underestimate the relationship between neighborhood and health, underscoring the importance of a life-course approach to cumulative exposure measurement.
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