Evidence map›Paper›PMID 38973195›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

"Abraxane-Like" Radiosensitizer for In Situ Oral Cancer Therapy.

Zijian Gong, Yixuan Fu, Yuan Gao, Fei Jiao, Qinzhi Su, Xiao Sang, Binglin Chen, Xuliang Deng, Xinyu Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. "Abraxane-Like" Radiosensitizer for In Situ Oral Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zijian GongCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.
Yixuan FuCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.
Yuan GaoCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.
Fei JiaoCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.
Qinzhi SuCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.
Xiao SangCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.
Binglin ChenCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.
Xuliang DengCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.
Xinyu LiuCentral Laboratory, Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material, Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China.ORCID 0000-0001-7495-442X

Funding

Beijing Nova Program Z211100002121013National Key R&D Program of China 2022YFC2405900National Key R&D Program of China 2022YFC2405903National Natural Science Foundation of China 81991505National Natural Science Foundation of China 82202327
6 · The paper itself

Abstract

Radiotherapy plays a vital role in cancer therapy. However, the hypoxic microenvironment of tumors greatly limits the effectiveness, thus it is crucial to develop a simple, efficient, and safe radiosensitizer to reverse hypoxia and ameliorate the efficacy of radiotherapy. Inspired by the structure of canonical nanodrug Abraxane, herein, a native HSA-modified CaO

Indexed as

Mouth NeoplasmsNanoparticlesRadiation-Sensitizing AgentsAnimalsCell Line, TumorDisease Models, AnimalHumansMiceMice, Inbred BALB CRadiation-Sensitizing Agentsbiomineralizationcalcium peroxideHSAoral cancerradiosensitizer

Identifiers

PMID38973195
PMCPMC11425904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.